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(R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%
(R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%
(R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%
Thermo Scientific Chemicals

(R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%

CAS: 2799-21-5 | C4H9NO | 87.122 g/mol
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Catalog number L19499.03
also known as L19499-03
Price (USD)
60.65
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Ends: 30-Jun-2026
70.70
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Quantity:
1 g
Request bulk or custom format
Price (USD)
60.65
Special offer
Online exclusive
Ends: 30-Jun-2026
70.70
Save 10.05 (14%)
Each
Chemical Identifiers
CAS2799-21-5
IUPAC Name(3R)-3-hydroxypyrrolidin-1-ium
Molecular FormulaC4H10NO
InChI KeyJHHZLHWJQPUNKB-SCSAIBSYSA-O
SMILESO[C@@H]1CC[NH2+]C1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless to yellow to orange-brown
FormViscous liquid
Assay (GC)≥97.5%
Identification (FTIR)Conforms
Optical Rotation+4.5° to +7.5° (c=3.5 in methanol)
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(R)-(+)-3-Hydroxypyrrolidine is used in the enantioselective addition of diethylzinc to aromatic aldehydes leading to optically active secondary alcohols. Also used to prepare-κ-opioid receptor agonists.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(R)-(+)-3-Hydroxypyrrolidine is used in the enantioselective addition of diethylzinc to aromatic aldehydes leading to optically active secondary alcohols. Also used to prepare-κ-opioid receptor agonists.

Solubility
Soluble in water and methanol.

Notes
Store under inert gas. It is sensitive to moisture. Store in a cool, dry conditions in well sealed containers. It is hygroscopic and sensitive to air. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. A Naylor.; D B Judd.; D I Scopes.; A G Hayes.; P J Birch. 4-[(Alkylamino)methyl]furo[3,2-c]pyridines: a new series of selective kappa-receptor agonists. Journal of Medicinal Chemistry. 1994, 37 (14), 2138-2144.
  2. Mitsunori Hashimoto.; Yutaka Eda.; Yasutomo Osanai.; Toshiaki Iwai.; Seiichi Aoki. A Novel Decarboxylation of α-amino acids. A Facile Method of Decarboxylation by the use of 2-Cyclohexen-1-one as a Catalyst. Chemistry Letters. 1986, 15 (6), 893-896.
  3. Product of Toray Industries, Inc.