'The derivatization of surfaces with bioactive molecules is a research area of growing importance for cell and tissue engineering. Tetherable molecules used in such applications must contain an anchoring moiety as well as the biofunctional group, typically along with a spacer to prevent steric clashes between the target molecule and ... More
Activity-dependent neurotransmitter-receptor matching at the neuromuscular junction.
AuthorsBorodinsky LN, Spitzer NC
JournalProc Natl Acad Sci U S A
PubMed ID17190810
'Signaling in the nervous system requires matching of neurotransmitter receptors with cognate neurotransmitters at synapses. The vertebrate neuromuscular junction is the best studied cholinergic synapse, but the mechanisms by which acetylcholine is matched with acetylcholine receptors are not fully understood. Because alterations in neuronal calcium spike activity alter transmitter specification ... More
Imaging the spread of reversible brain inactivations using fluorescent muscimol.
AuthorsAllen TA, Narayanan NS, Kholodar-Smith DB, Zhao Y, Laubach M, Brown TH,
JournalJ Neurosci Methods
PubMed ID18377997
Muscimol is a GABA A-agonist that causes rapid and reversible suppression of neurophysiological activity. Interpretations of the effects of muscimol infusions into the brain have been limited because of uncertainty about spread of the drug around the injection site. To solve this problem, the present study explored the use of ... More
GABA(A) receptor binding and localization in the tiger salamander retina.
AuthorsWang H, Standifer KM, Sherry DM
JournalVis Neurosci
PubMed ID10750823
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the retina and also appears to act as a trophic factor regulating photoreceptor development and regeneration. Although the tiger salamander is a major model system for the study of retinal circuitry and regeneration, our understanding of GABA receptors in this species ... More
A cross-modality enhancement of defensive flight via parvalbumin neurons in zona incerta.
Authors
JournalElife
PubMed ID30985276
Theta Oscillations during Active Sleep Synchronize the Developing Rubro-Hippocampal Sensorimotor Network.
Authors
JournalCurr Biol
PubMed ID28479324
The higher order auditory cortex is involved in the assignment of affective value to sensory stimuli.
Authors
JournalNat Commun
PubMed ID26619940
Thalamic input to motor cortex facilitates goal-directed action initiation.
Authors
JournalCurr Biol
PubMed ID34302741
The anterior cingulate cortex directly enhances auditory cortical responses in air-puffing-facilitated flight behavior.
Authors
JournalCell Rep
PubMed ID35263590
Contextual and cross-modality modulation of auditory cortical processing through pulvinar mediated suppression.
Authors
JournalElife
PubMed ID32142411
Coordinated increase of reliable cortical and striatal ensemble activations during recovery after stroke.
Authors
JournalCell Rep
PubMed ID34260929
Thalamic Regulation of Sucrose Seeking during Unexpected Reward Omission.
Authors
JournalNeuron
PubMed ID28426970
General Anesthesia Decouples Cortical Pyramidal Neurons.
Authors
JournalCell
PubMed ID32084339
A cerebellar-thalamocortical pathway drives behavioral context-dependent movement initiation.