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Thermo Scientific™

Proteome Discoverer™ Software

 Related applications:
Industrial Mass Spectrometry

Identify and quantify proteins in complex biological samples using Thermo Scientific™ Proteome Discoverer™ software. Proteome Discoverer software simplifies a wide range of proteomics workflows, from protein and peptide identification to PTM analysis to isobaric mass tagging and both SILAC and label-free quantitation. It supports multiple database search algorithms (SEQUEST, Z-Core, Mascot, and Byonic) and multiple dissociation techniques (CID, HCD, ETD, and EThcD) for more comprehensive analyses.

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Proteome Discoverer software supports multiple dissociation techniques, quantitation technologies, and database search algorithms for comprehensive protein identification, characterization, and quantitation.

  • Provides a choice of search algorithms (SEQUEST, Z-Core, Mascot Byonic, etc.) and can combine output from multiple algorithms to maximize and cross-validate results
  • Supports multiple dissociation techniques (CID, HCD, and ETD) for more complete coverage and confident identification of PTMs
  • Supports isobaric mass tagging (TMT, iTRAQ) and heavy-peptide techniques, enabling relative or absolute quantitation
  • Validates protein IDs with false discovery rate (FDR) determination
Productive and Expandable
  • Automates data analysis, and simplifies MSn data analysis through wizards and customizable workflows
  • Provides effective location of low-level sample components using creative data interrogation strategies such as generating inclusion and exclusion lists and importing those lists directly into instrument methods
  • Illustrates biological context by automatically annotating identified proteins with GO classifications, PTMs sites, and literature references from public databases
  • Facilitates data comparison, exchange, and verification with support for data standards developed by the HUPO Proteomics Standards Initiative (PSI) 
  • Provides a seamless transition from Thermo Scientific™ BioWorks™ platform using the SRF file import wizard
  • Expands through the integration of custom software tools
  • Supports third party nodes for data prcessing, and enables processing of large datasets and persistent reports
  • Fast, robust algorithms for peak selection and peptide quantification to extract the maximum possible information from quantitative proteomics studies
  • Obtain reliable statistics and validate quantification results visually

Specifications, terms, and pricing are subject to change. Not all products are available in all countries. Please consult your local sales representative for details.

Compound discoverer 3.0 Software coming soon

Compound Discoverer 3.0 Software coming soon

Learn more ›


Manuals & protocols