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PRKCQ (PKC theta) Recombinant Human Protein

Catalog number: P2996

 Related applications: Protein Assays and Analysis | Target & Lead Identification & Validation

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Description

The PKC family of serine⁄threonine kinases, including PRKCQ (PKC theta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Gene ID: 5584, 5588
Species: Human
Target Gene: protein kinase C, theta
Gene Aliases: PRKCQ (PKC theta)
Kinase Group: Ser⁄Thr Kinases: AGC Group
Product Size: 5 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Serine⁄Threonine Kinases
Accession Number: NP_006248
Molecular Weight: 84.4 kDa
Research Category: Signal Transduction
System Compatibility: LanthaScreen® Substrate, LanthaScreen® Antibody, Z'-LYTE™, Omnia® Bulk Substrate
Validated Application: Kinase Assay
Protein Tag or Fusion: His Tag
Expression: Baculovirus
Kinase Family: PKC Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 20mM HEPES, pH 7.5, 150mM NaCl, 0.5mM EGTA, 0.5mM EDTA, 0.05% NP-40, 5mM DTT, 20% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.

Documents

Manuals & protocols