Thermo Scientific PEPotec Immuno Custom Peptide Libraries are fully synthetic custom libraries that support high-throughput screening assays to map epitopes or identify immunogenic sites in proteins. They are fully customizable and supplied with acetate as the counter-ion to avoid potential toxicity issues in epitope discovery and mapping. These application-specific peptide libraries are ready to use in applications such as vaccine development, T- and-B cell research, antibody development, and biomarker discovery. Optional peptide modifications are available, including residue phosphorylation and acetylation, and different formulations are possible that enable study of cellular signaling events.
Highlights: • Low toxicity—peptides with acetate as the counter-ion are less toxic in certain applications when compared with those with trifluoroacetate (TFA) • Application-specific—the 6- to 20–amino acid peptide length distribution fits most immunological applications • Convenient—peptides are provided in individual 2-D barcoded tubes in 96-tube plates, and each order includes a CD with the peptide sequences and positions in each plate • Flexible—optional services, including phosphorylation and acetylation, are available for studying signaling and regulatory proteins
Applications: • Epitope mapping of B and T cells • Vaccine development • High-throughput peptide screening • Biomarker discovery • Cell signaling (kinase/protease studies)