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The PKC family of serine⁄threonine kinases, including PRKCQ (PKC theta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
For Research Use Only. Not for use in diagnostic procedures.
Ser⁄Thr Kinases: AGC Group
90% by SDS-PAGE
PRKCQ (PKC theta)
PKC Kinase Family
Contents & Storage
Storage Buffer: 20mM HEPES, pH 7.5, 150mM NaCl, 0.5mM EGTA, 0.5mM EDTA, 0.05% NP-40, 5mM DTT, 20% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.