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The PKC family of serine⁄threonine kinases, including PRKCQ (PKC theta), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NP_006248
Kinase Group
Ser⁄Thr Kinases: AGC Group
Shipping Condition
Dry Ice
Expression System
Baculovirus
Form
Frozen
Protein Form
Full Length
Research Category
Drug Development
Species
Human
Validated Application
Kinase Assay
Molecular Weight
84.4 kDa
Purity
90% by SDS-PAGE
Quantity
1 mg
Gene Alias
PRKCQ (PKC theta)
KinaseFamily
PKC Kinase Family
Recombinant
Yes
Protein Tag
His Tag
Contents & Storage
Storage Buffer: 20mM HEPES, pH 7.5, 150mM NaCl, 0.5mM EGTA, 0.5mM EDTA, 0.05% NP-40, 5mM DTT, 20% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
