LanthaScreen® Tb-anti-PRAS40 [pSer183] Antibody

Catalog number: PV5578

 Related applications: Pharma & Biopharma | Target & Lead Identification & Validation

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Description

A part of the PI3K⁄AKT Pathway, PRAS40 (Proline-rich AKT substrate, 40 kDa) is a cytosolic protein that is phosphorylated at position Ser183. PRAS40 has been shown to bind to the mTORC1 complex and inhibit downstream signaling (i.e., phosphorylation of 4E-BP1 or p70S6K).
For use in combination with the LanthaScreen® PRAS40 HEK293E cell line (K1528) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Readout: End Point
Reactivity: Human
Target Gene: Ser/Thr Kinases
Label or Dye: Tb (Terbium)
Product Size: 25 µg
Excitation⁄Emission (nm): 340⁄490, 520
Shipping Condition: Dry Ice

Contents & storage

Terbium-labeled pPRAS40 (pSer183) antibody in HEPES buffered saline. Store at -20°C.

Documents

Manuals & protocols