Thermo Scientific™

Lab Vision™ CD8, Rabbit Monoclonal Antibody

Related applications:

Anatomical Pathology

Ensure accurate, reproducible results in immunohistochemistry applications with Thermo Scientific™ CD8, Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

 

Back to top
CD8 molecule consists of two chains, termed α and β chain, which are expressed as a disulphide-linked α/β heterdimer or as an α/α homodimer on T cell subset, thymocytes and NK cells. The majority of CD8+ T cells express CD8 as α/β heterdimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 alpha chain (but not β chain).

Host Species: Rabbit

Clone: SP16

Species Reactivity: Human. Others not tested.

Epitope: C-terminus

Immunogen: Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of α-chain of the CD8 molecule

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)