Thermo Scientific™

Pentafluoropropanol Acylation Reagent

Related applications:

Industrial Chromatography

Enhance electron-capture detection (ECD) and improve GC-MS analysis by using Thermo Scientific™ Pentafluoropropanol Acylation Reagent for derivatization. This acylation reagent reacts readily with alcohols, phenols, and amines to produce perfluoroacyl derivatives which improve ECD response and provide useful structural information for GC-MS applications. Carboxylic acids can be derivatized using a two-step reaction, which involves a reaction with an anhydride followed by a fluorinated alcohol. This derivatization reagent is well suited for confirmation of drugs of abuse.
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  • Addition of fluorine atoms into compounds greatly enhances the sensitivity of certain detectors for all those materials
  • Carboxylic acids can be derivatized using a two-step reaction involving reaction with anhydride, followed by a fluorinated alcohol