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Valinomycin

Catalog number: V1644

Molecular Probes™  Related applications: Cell Viability, Proliferation & Function

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Description

Valinomycin is a natural, lipid-soluble molecule (Mr = ~1,110) that binds potassium ions (K+) and facilitates their transfer across lipid bilayers (i.e., it is an ionophore). It is a macrocyclic molecule formed from 12 alternating amino acids and esters, synthesized by specific Streptomyces. Valinomycin exhibits a 10,000-fold selectivity for K+ over Na+. Valinomycin is a potent antibiotic. It is commonly used as an agent to induce apoptosis and can also be used to calibrate potentiometric responses in membrane experiments involving potential-sensitive dyes such as di-4-ANEPPS.


• K+ selective ionophore
• Neutrally charged
• Soluble in ethanol, DMSO, etc., but insoluble in water


For Research Use Only. Not for human or animal therapeutic or diagnostic use.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Indicator Type: Ionophore
Product Size: 25 mg
Shipping Condition: Room Temperature

Contents & storage

Store in freezer (-5 to -30°C) and protect from light.

Documents

Manuals & protocols

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