DNase X is a glycosylphosphatidylinositol-anchored membrane enzyme that provides a barrier to endocytosis-mediated transfer of a foreign gene.
Authors:Shiokawa D, Matsushita T, Shika Y, Shimizu M, Maeda M, Tanuma S
Journal:J Biol Chem
PubMed ID:17416904
'DNase X is the first mammalian DNase to be isolated that is homologous to DNase I. In this study, we have examined its function using a novel monoclonal antibody and showed it to be expressed on the cell surface as a glycosylphosphatidylinositolanchored membrane protein. High level expression was observed in ... More