Search Thermo Fisher Scientific
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PA5-14461 targets CLK4 in WB and FACS applications and shows reactivity with Human and Mouse samples.
The PA5-14461 immunogen is a synthetic peptide from the N-terminal region of CLK4 conjugated to KLH.
PA5-14461 detects CLK4 which has a predicted molecular weight of approximately 57 kDa.
CLK4 belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5, a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase.
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