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Digital PCR
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› Hs000000004_rm
See other BRAF DPCR Assay's ›
Gene:
BRAF
Transcript:
ENST00000288602.0
Assay Name:
BRAF_476
COSMIC ID:
476
Nucleotide Mutation:
c.1799T>A
Amino Acid Change
p.V600E
Mutation genome location:
chr.7 140753336 on build GRCh38
Assay gene location:
Overlaps Intron 15 - Exon 16
Context Sequence [VIC/FAM]:
ATGGGACCCACTCCATCGAGATTTC
[A/T]
CTGTAGCTAGACCAAAATCACCTAT
Assay ID
Hs000000004_rm
Size
S: 450 rxns
S: 450 rxns
Availability
Made To Order
Catalog #
A44177
Price
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More Information
Set Membership:
Coding - Overlap Exon/Intron
Panther Classification:
Molecular Function -
kinase
non-receptor serine/threonine protein kinase
non-receptor tyrosine protein kinase
protein kinase
transferase
Gene Ontology Categories:
Function(s)
Process(es)
MAPK cascade
activation of MAPKK activity
myeloid progenitor cell differentiation
protein phosphorylation
visual learning
organ morphogenesis
positive regulation of gene expression
negative regulation of fibroblast migration
glucose transport
thyroid gland development
positive regulation of peptidyl-serine phosphorylation
somatic stem cell population maintenance
cellular response to drug
regulation of cell proliferation
negative regulation of apoptotic process
CD4-positive, alpha-beta T cell differentiation
positive T cell selection
response to peptide hormone
negative regulation of neuron apoptotic process
thymus development
positive regulation of axon regeneration
positive regulation of axonogenesis
protein heterooligomerization
positive regulation of stress fiber assembly
response to cAMP
long-term synaptic potentiation
head morphogenesis
face development
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
establishment of protein localization to membrane
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of synaptic vesicle exocytosis
negative regulation of endothelial cell apoptotic process
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
small GTPase binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity
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