Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: AGDIQQLLQ LQQLVLVPGH HLQPPAQFLL PQAQQSQPGL LPTPNLFQLP QQTQGALLTS QPRAGLPTQP PKCLEPPSHP EEPSDLEELE QFARTFKQRR IKLGFTQGDV GLAMGKLYGN DFSQTTISRF EALNLSFKNM CKLKPLLEKW LNDAETMSVD SSLPSPNQLS SPSLGFDGLP GRRRKKRTSI ETNVRFALEK SFLANQKPTS EEILLIAEQL HMEKEVIRVW FCNRRQKEKR INPCSAAPML PSPGKPASYS PHMVTPQGGA GTLPLSQASS SLSTTAQTPA LKAATRLSAC QA (100-400 aa encoded by BC006101)
OCT-2 is a transcription factor belonging to the POU homeo-domain family that binds to the Ig gene octamer sites regulating B cell specific genes. OCT-2 protein expression is not restricted to B cells, although expression levels are much higher in these cells. OCT-2 expression is reported to be significantly greater in germinal center derived lymphomas, although other B cell lymphomas also display high levels of expression.
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Protein Aliases: homeobox protein; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Oct-2; Octamer-binding protein 2; Octamer-binding transcription factor 2; OTF-2; POU domain, class 2, transcription factor 2
Gene Aliases: Oct-2; OCT2; Oct2a; Oct2b; Otf-2; OTF2; POU2F2
UniProt ID: (Human) P09086, (Mouse) Q00196
Entrez Gene ID: (Human) 5452, (Mouse) 18987
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