Product References
Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity.
Immunity
DiToro D,Harbour SN,Bando JK,Benavides G,Witte S,Laufer VA,Moseley C,Singer JR,Frey B,Turner H,Bruning J,Darley-Usmar V,Gao M,Conover C,Hatton RD,Frank S,Colonna M,Weaver CT
11-7042 was used in Flow cytometry/Cell sorting to show that, among effector T cell subsets, Th17 and Treg cells selectively expressed multiple components of the IGF system.
Tue Apr 14 00:00:00 EDT 2020
NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis.
PLoS pathogens
Kastelberg B,Tubau-Juni N,Ayubi T,Leung A,Leber A,Hontecillas R,Bassaganya-Riera J,Kale SD
11-7042 was used in Flow cytometry/Cell sorting to point strongly towards the cell-specific and contextual function of Nlrx1 during invasive pulmonary aspergillosis and may lead to novel therapeutics to reduce Th2 responses by CD103+ DCs or heightened recruitment of neutrophils.
Tue Sep 01 00:00:00 EDT 2020
NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis.
PLoS pathogens
Kastelberg B,Tubau-Juni N,Ayubi T,Leung A,Leber A,Hontecillas R,Bassaganya-Riera J,Kale SD
11-7042 was used in Flow cytometry/Cell sorting to point strongly towards the cell-specific and contextual function of Nlrx1 during invasive pulmonary aspergillosis and may lead to novel therapeutics to reduce Th2 responses by CD103+ DCs or heightened recruitment of neutrophils.
Tue Sep 01 00:00:00 EDT 2020
IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury.
Journal of immunology (Baltimore, Md. : 1950)
Miao W,Zhao Y,Huang Y,Chen D,Luo C,Su W,Gao Y
11-7042 was used in Flow cytometry/Cell sorting to demonstrate that IL-13 treatment improved neurologic outcomes after Traumatic Brain Injury through adjusting microglia/macrophage phenotypes and inhibiting inflammatory responses.
Sun Mar 15 00:00:00 EDT 2020
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using IL-4 monoclonal antibody (Product # 11-7042-41) in Flow Cytometry
Wed Feb 01 00:00:00 EST 2017
Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells.
Scientific reports
Wang H,Lin J,Zeng L,Ouyang C,Ran P,Yang P,Liu Z
Published figure using IL-4 monoclonal antibody (Product # 11-7042-41) in ELISA
Thu Aug 17 00:00:00 EDT 2017
T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.
Nature immunology
Martin BN,Wang C,Zhang CJ,Kang Z,Gulen MF,Zepp JA,Zhao J,Bian G,Do JS,Min B,Pavicic PG,El-Sanadi C,Fox PL,Akitsu A,Iwakura Y,Sarkar A,Wewers MD,Kaiser WJ,Mocarski ES,Rothenberg ME,Hise AG,Dubyak GR,Ransohoff RM,Li X
11704241 was used in flow cytometry to investigate the role of IL-1beta produced by a T helper 17 cell-intrinsic ASC-NLRP3-caspase-8 inflammasome in experimental autoimmune encephalomyelitis
Sun May 01 00:00:00 EDT 2016
Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4.
Nature communications
Gomez-Rodriguez J,Meylan F,Handon R,Hayes ET,Anderson SM,Kirby MR,Siegel RM,Schwartzberg PL
11-7042 was used in Flow cytometry/Cell sorting to investigate the role of IL-9 in allergic asthma and autoimmunity, showing that Itk is required for Th9 differentiation via TCR-mediated induction of IL-2 and IRF4.
Thu Mar 03 00:00:00 EST 2016
Anti-G-CSF treatment induces protective tumor immunity in mouse colon cancer by promoting protective NK cell, macrophage and T cell responses.
Oncotarget
Morris KT,Castillo EF,Ray AL,Weston LL,Nofchissey RA,Hanson JA,Samedi VG,Pinchuk IV,Hudson LG,Beswick EJ
11-7042 was used in Flow cytometry/Cell sorting to indicate a crucial role for G-CSF inhibition in promoting protective anti-tumor immunity.
Tue Sep 08 00:00:00 EDT 2015
Obesity enhances Th2 inflammatory response via natural killer T cells in a murine model of allergic asthma.
International journal of clinical and experimental medicine
Chen YP,Zhang JH,Li CQ,Sun QX,Jiang XH
11-7042 was used in Flow cytometry/Cell sorting to investigate the mechanisms connecting the development of asthma and obesity.
Wed Dec 02 00:00:00 EST 2015
Prophylaxis with a respiratory syncytial virus (RSV) anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice.
Journal of virology
Boyoglu-Barnum S,Chirkova T,Todd SO,Barnum TR,Gaston KA,Jorquera P,Haynes LM,Tripp RA,Moore ML,Anderson LJ
11-7042 was used in Flow cytometry/Cell sorting to suggest that the RSV G protein not only contributes to disease, but also dampens the host immune response to infection.
Mon Sep 01 00:00:00 EDT 2014
Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
Nature immunology
Islam SA,Chang DS,Colvin RA,Byrne MH,McCully ML,Moser B,Lira SA,Charo IF,Luster AD
11-7042 was used in Flow cytometry/Cell sorting to investigate the biological activity of CCL8, showing that it promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
Tue Feb 01 00:00:00 EST 2011
PIPKI gamma 90 negatively regulates LFA-1-mediated adhesion and activation in antigen-induced CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Wernimont SA,Legate KR,Simonson WT,Fassler R,Huttenlocher A
11-7042 was used in Flow cytometry/Cell sorting to demonstrate the activity of PIPKI gamma 90 as a novel negative regulator of antigen-induced CD4+ T cell adhesion and activation.
Fri Oct 15 00:00:00 EDT 2010
Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses.
Journal of immunology (Baltimore, Md. : 1950)
Walsh KP,Brady MT,Finlay CM,Boon L,Mills KH
11-7042 was used in Flow cytometry/Cell sorting to provide evidence that parasites can exert bystander immunosuppression of pathogenic T cells that mediate autoimmune diseases.
Sat Aug 01 00:00:00 EDT 2009
Protein kinase B/Akt signals impair Th17 differentiation and support natural regulatory T cell function and induced regulatory T cell formation.
Journal of immunology (Baltimore, Md. : 1950)
Pierau M,Engelmann S,Reinhold D,Lapp T,Schraven B,Bommhardt UH
11-7042 was used in Flow cytometry/Cell sorting to indicate an important role of PKB signals on control of TGF-beta1-mediated T cell responses and, thereby, on tolerizing and inflammatory immune processes.
Sun Nov 15 00:00:00 EST 2009
Galectin-1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 function.
European journal of immunology
Motran CC,Molinder KM,Liu SD,Poirier F,Miceli MC
11-7042 was used in Flow cytometry/Cell sorting to identify galectin-1 as a cross-regulatory cytokine that selectively antagonizes Th1 survival, while promoting TCR-induced Th2 cytokine production.
Sat Nov 01 00:00:00 EDT 2008
Role of Valpha14+ NKT cells in the development of Hepatitis B virus-specific CTL: activation of Valpha14+ NKT cells promotes the breakage of CTL tolerance.
International immunology
Ito H,Ando K,Ishikawa T,Nakayama T,Taniguchi M,Saito K,Imawari M,Moriwaki H,Yokochi T,Kakumu S,Seishima M
11-7042 was used in Flow cytometry/Cell sorting to open up a new method for clearing the virus from patients with persistent HBV infection.
Tue Jul 01 00:00:00 EDT 2008
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17.
Journal of leukocyte biology
Nakae S,Iwakura Y,Suto H,Galli SJ
11-7042 was used in Functional assays to compare the cell surface marker expression profiles of Th1 and Th17 cells.
Tue May 01 00:00:00 EDT 2007