Product References
Notch Signaling Activates Stem Cell Properties of Müller Glia through Transcriptional Regulation and Skp2-mediated Degradation of p27Kip1.
PloS one
Del Debbio CB,Mir Q,Parameswaran S,Mathews S,Xia X,Zheng L,Neville AJ,Ahmad I
51-1900 was used in immunocytochemistry, immunohistochemistry, and western blot to study how transcriptional regulation and Skp2-mediated degradation of p27Kip1 activates stem cell properties of muller glia through notch signaling
Thu Aug 11 00:00:00 EDT 2016
Notch Signaling Activates Stem Cell Properties of Müller Glia through Transcriptional Regulation and Skp2-mediated Degradation of p27Kip1.
PloS one
Del Debbio CB,Mir Q,Parameswaran S,Mathews S,Xia X,Zheng L,Neville AJ,Ahmad I
51-1900 was used in immunocytochemistry, immunohistochemistry, and western blot to study how transcriptional regulation and Skp2-mediated degradation of p27Kip1 activates stem cell properties of muller glia through notch signaling
Thu Aug 11 00:00:00 EDT 2016
The physiological significance of p27(KIP1) expression in detrusor function.
The Journal of urology
Niederhoff RA,Manson SR,Tawfik A,Austin PF
51-1900 was used in western blot to elucidate the role of p27(KIP1) in the structure and function of the detrusor layer of the bladder wall
Fri Oct 01 00:00:00 EDT 2010
The human papillomavirus type 18 E2 protein is a cell cycle-dependent target of the SCFSkp2 ubiquitin ligase.
Journal of virology
Bellanger S,Tan CL,Nei W,He PP,Thierry F
51-1900 was used in immunoprecipitation and western blot to study human papillomavirus type 18 E2 degradation
Fri Jan 01 00:00:00 EST 2010
Mechanoregulation of proliferation.
Molecular and cellular biology
Jiang X,Austin PF,Niederhoff RA,Manson SR,Riehm JJ,Cook BL,Pengue G,Chitaley K,Nakayama K,Nakayama KI,Weintraub SJ
51-1900 was used in western blot to examine the role of Skp2 in the development of mechanical tension
Tue Sep 01 00:00:00 EDT 2009
Disrupting Skp2-cyclin A interaction with a blocking peptide induces selective cancer cell killing.
Molecular cancer therapeutics
Ji P,Sun D,Wang H,Bauzon F,Zhu L
51-1900 was used in flow cytometry, immunocytochemistry, and western blot to report that the Skp2-cyclin A interaction has a major role in cancer cell survival
Thu Feb 01 00:00:00 EST 2007
Skp2 contains a novel cyclin A binding domain that directly protects cyclin A from inhibition by p27Kip1.
The Journal of biological chemistry
Ji P,Goldin L,Ren H,Sun D,Guardavaccaro D,Pagano M,Zhu L
51-1900 was used in western blot to determine the consequences of the Skp2-cyclin A interaction
Fri Aug 18 00:00:00 EDT 2006
Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2.
Molecular and cellular biology
Liang M,Liang YY,Wrighton K,Ungermannova D,Wang XP,Brunicardi FC,Liu X,Feng XH,Lin X
Wed Sep 01 00:00:00 EDT 2004
Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2.
Molecular and cellular biology
Liang M,Liang YY,Wrighton K,Ungermannova D,Wang XP,Brunicardi FC,Liu X,Feng XH,Lin X
Wed Sep 01 00:00:00 EDT 2004
Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2.
Molecular and cellular biology
Liang M,Liang YY,Wrighton K,Ungermannova D,Wang XP,Brunicardi FC,Liu X,Feng XH,Lin X
Wed Sep 01 00:00:00 EDT 2004
Skp2 regulates Myc protein stability and activity.
Molecular cell
Kim SY,Herbst A,Tworkowski KA,Salghetti SE,Tansey WP
51-1900 was used in western blot to report that Skp2 regulates Myc ubiquitination and stability.
Thu May 01 00:00:00 EDT 2003
Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
Endocrinology
Lin R,Wang TT,Miller WH,White JH
Sat Mar 01 00:00:00 EST 2003
Inhibition of F-Box protein p45(SKP2) expression and stabilization of cyclin-dependent kinase inhibitor p27(KIP1) in vitamin D analog-treated cancer cells.
Endocrinology
Lin R,Wang TT,Miller WH,White JH
Sat Mar 01 00:00:00 EST 2003
The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(Skp2).
Genes & development
Tedesco D,Lukas J,Reed SI
Fri Nov 15 00:00:00 EST 2002