Product References
Inauhzin sensitizes p53-dependent cytotoxicity and tumor suppression of chemotherapeutic agents.
Neoplasia (New York, N.Y.)
Zhang Y,Zhang Q,Zeng SX,Hao Q,Lu H
MA5-14353 was used in western blot to study the ability of a small molecule p53 activator to sensitize tumor cells to cisplatin and doxorubicin chemotherapy
Wed May 01 00:00:00 EDT 2013
Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1.
The EMBO journal
Sun XX,Challagundla KB,Dai MS
MA5-14353 was used in western blot to study the positive regulation of p53 stability by the deubiquitinating enzyme Otubain 1
Wed Feb 01 00:00:00 EST 2012
The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer.
Cancer letters
Roh JL,Ko JH,Moon SJ,Ryu CH,Choi JY,Koch WM
MA5-14353 was used in western blot to study the enhancement of cisplatin-induced cytotoxicity and apoptosis in head and neck cancer by a p53-reactivating small-molecule
Sat Dec 01 00:00:00 EST 2012
MicroRNA-223 regulates FOXO1 expression and cell proliferation.
FEBS letters
Wu L,Li H,Jia CY,Cheng W,Yu M,Peng M,Zhu Y,Zhao Q,Dong YW,Shao K,Wu A,Wu XZ
MA5-14353 was used in western blot to study the effects of microRNA-223 overexpression on the expression of FOXO1 and on cell proliferation
Thu Apr 05 00:00:00 EDT 2012
p53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma.
Oral oncology
Roh JL,Kang SK,Minn I,Califano JA,Sidransky D,Koch WM
MA5-14353 was used in western blot to study the effects of small molecule p53 reactivators on apoptosis and on the efficacy of chemotherapy agents in head and neck squamous cell carcinoma
Sat Jan 01 00:00:00 EST 2011
CyclinD1, p53, E-cadherin, and VEGF discordant expression in paired regional metastatic lymph nodes of esophageal squamous cell carcinoma: a tissue array analysis.
Journal of surgical oncology
Luo KJ,Hu Y,Wen J,Fu JH
MA5-14353 was used in immunohistochemistry to characterize expression of biomarkers in carcinomas
Thu Sep 01 00:00:00 EDT 2011
Interplay between ribosomal protein S27a and MDM2 protein in p53 activation in response to ribosomal stress.
The Journal of biological chemistry
Sun XX,DeVine T,Challagundla KB,Dai MS
MA5-14353 was used in western blot to study the role of ribosomal protein S27a and MDM2 in p53 activation in response to ribosomal stress
Fri Jul 01 00:00:00 EDT 2011
4'-Chloro-3,5-dihydroxystilbene, a resveratrol derivative, induces lung cancer cell death.
Acta pharmacologica Sinica
Wu JY,Tsai KW,Shee JJ,Li YZ,Chen CH,Chuang JJ,Liu YW
MA5-14353 was used in western blot to study the antitumor effect of the resveratrol derivative 4'-chloro-3,5-dihydroxystilbene on a lung adenocarcinoma cell line
Fri Jan 01 00:00:00 EST 2010
Aurora A selective inhibitor MLN8237 suppresses the growth and survival of HTLV-1-infected T-cells in vitro.
Cancer science
Tomita M,Mori N
MA5-14353 was used in western blot to study the effect of a selective Aurora A kinase inhibitor on the viability, growth and apoptosis of HTLV-1-infected T-cells
Sat May 01 00:00:00 EDT 2010
Human testicular orphan receptor 4 enhances thyroid hormone receptor signaling.
Journal of cellular physiology
Huang YH,Liao CH,Chen RN,Liao CJ,Lin KH
MA5-14353 was used in western blot to investigate the effect of testicular orphan receptor 4 on thyroid hormone receptor signal regulation
Mon Feb 01 00:00:00 EST 2010
The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions.
Molecular and cellular biology
Yuan Z,Villagra A,Peng L,Coppola D,Glozak M,Sotomayor EM,Chen J,Lane WS,Seto E
MA5-14353 was used in western blot to study the ability of TRIM29 to bind p53 and repress p53-regulated gene expression
Tue Jun 01 00:00:00 EDT 2010
EBV-positive Hodgkin lymphoma is associated with suppression of p21cip1/waf1 and a worse prognosis.
Molecular cancer
Liu TY,Wu SJ,Huang MH,Lo FY,Tsai MH,Tsai CH,Hsu SM,Lin CW
MA5-14353 was used in western blot to investigate the association between EBV+ HLs and suppression of p21cip1/waf1 and its prognostic significance
Tue Feb 09 00:00:00 EST 2010
Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein.
The Journal of biological chemistry
Yuan Z,Peng L,Radhakrishnan R,Seto E
MA5-14353 was used in western blot to study the ability of HDAC9 to deacetylate and regulate the function of the ATDC (TRIM29) protein
Fri Dec 10 00:00:00 EST 2010
p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.
DNA repair
Cazzalini O,Donà F,Savio M,Tillhon M,Maccario C,Perucca P,Stivala LA,Scovassi AI,Prosperi E
MA5-14353 was used in immunocytochemistry to study the role of poly(ADP-ribose) polymerase-1 in the mechanism by which p21CDKN1A participates in base excision repair
Fri Jun 04 00:00:00 EDT 2010
Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2.
Hepatology (Baltimore, Md.)
Frémin C,Bessard A,Ezan F,Gailhouste L,Régeard M,Le Seyec J,Gilot D,Pagès G,Pouysségur J,Langouët S,Baffet G
MA5-14353 was used in western blot to study the distinct roles of ERK1 and ERK2 in regulating the cell cycle and long-term survival in normal hepatocytes
Sun Mar 01 00:00:00 EST 2009
Degradation of p21CDKN1A after DNA damage is independent of type of lesion, and is not required for DNA repair.
DNA repair
Savio M,Coppa T,Cazzalini O,Perucca P,Necchi D,Nardo T,Stivala LA,Prosperi E
MA5-14353 was used in western blot to study the degradation of p21CDKN1A after DNA damage
Sat Jul 04 00:00:00 EDT 2009
Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer.
The Prostate
Chu JH,Yu S,Hayward SW,Chan FL
MA5-14353 was used in immunocytochemistry and western blot to evaluate a three-dimensional prostatic epithelial cell culture model for the study of epithelial-mesenchymal transition
Sun Mar 01 00:00:00 EST 2009
Development of a three-dimensional culture model of prostatic epithelial cells and its use for the study of epithelial-mesenchymal transition and inhibition of PI3K pathway in prostate cancer.
The Prostate
Chu JH,Yu S,Hayward SW,Chan FL
MA5-14353 was used in immunocytochemistry and western blot to evaluate a three-dimensional prostatic epithelial cell culture model for the study of epithelial-mesenchymal transition
Sun Mar 01 00:00:00 EST 2009
p53-dependent antiproliferative and antitumor effect of novel alkyl series of diorganotin(IV) compounds.
Investigational new drugs
Koch B,Basu Baul TS,Chatterjee A
MA5-14353 was used in western blot to investigate the effect of diorganotin dichloride complexes on tumor growth
Sat Aug 01 00:00:00 EDT 2009
Puerariae radix isoflavones and their metabolites inhibit growth and induce apoptosis in breast cancer cells.
Biochemical and biophysical research communications
Lin YJ,Hou YC,Lin CH,Hsu YA,Sheu JJ,Lai CH,Chen BH,Lee Chao PD,Wan L,Tsai FJ
MA5-14353 was used in western blot to study the effect of Puerariae radix isoflavones on growth and apoptosis in breast cancer cells
Fri Jan 23 00:00:00 EST 2009
ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair.
Cancer chemotherapy and pharmacology
Stordal B,Davey R
MA5-14353 was used in western blot to investigate the mechanism for platinum resistance in specific cell lines and the involvement of ERCC1 and RAD51B proteins
Sun Mar 01 00:00:00 EST 2009
Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence.
Cell cycle (Georgetown, Tex.)
Perucca P,Cazzalini O,Madine M,Savio M,Laskey RA,Vannini V,Prosperi E,Stivala LA
MA5-14353 was used in immunocytochemistry and western blot to investigate the importance of p21 in quiescence entry and maintenance
Thu Jan 01 00:00:00 EST 2009
Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence.
Cell cycle (Georgetown, Tex.)
Perucca P,Cazzalini O,Madine M,Savio M,Laskey RA,Vannini V,Prosperi E,Stivala LA
MA5-14353 was used in immunocytochemistry and western blot to investigate the importance of p21 in quiescence entry and maintenance
Thu Jan 01 00:00:00 EST 2009
HER2 carboxyl-terminal fragments regulate cell migration and cortactin phosphorylation.
The Journal of biological chemistry
García-Castillo J,Pedersen K,Angelini PD,Bech-Serra JJ,Colomé N,Cunningham MP,Parra-Palau JL,Canals F,Baselga J,Arribas J
MA5-14353 was used in western blot to study the regulation of cell migration and cortactin phosphorylation by HER2 carboxyl-terminal fragments and the significance for beast cancer metastasis
Fri Sep 11 00:00:00 EDT 2009
Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair.
Nucleic acids research
Cazzalini O,Perucca P,Savio M,Necchi D,Bianchi L,Stivala LA,Ducommun B,Scovassi AI,Prosperi E
MA5-14353 was used in immunoprecipitation and western blot to study the role of the cell cycle inhibitor p21(CDKN1A) in regulating nucleotide excision repair
Sat Mar 01 00:00:00 EST 2008
Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair.
Nucleic acids research
Cazzalini O,Perucca P,Savio M,Necchi D,Bianchi L,Stivala LA,Ducommun B,Scovassi AI,Prosperi E
MA5-14353 was used in immunoprecipitation and western blot to study the role of the cell cycle inhibitor p21(CDKN1A) in regulating nucleotide excision repair
Sat Mar 01 00:00:00 EST 2008
Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America
Killilea DW,Ames BN
MA5-14353 was used in western blot to study the effect of magnesium deficiency on cultured human fibroblast cellular senescence
Tue Apr 15 00:00:00 EDT 2008
Orphan nuclear receptor estrogen-related receptor-beta suppresses in vitro and in vivo growth of prostate cancer cells via p21(WAF1/CIP1) induction and as a potential therapeutic target in prostate cancer.
Oncogene
Yu S,Wong YC,Wang XH,Ling MT,Ng CF,Chen S,Chan FL
MA5-14353 was used in western blot to study the mechanism by which the orphan nuclear receptor ERR-beta suppresses prostate cancer growth
Thu May 22 00:00:00 EDT 2008
Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation.
Free radical biology & medicine
Shukla S,Gupta S
MA5-14353 was used in western blot to study the role of ROS and p53 activation in apigenin-induced prostate cancer cell death
Thu May 15 00:00:00 EDT 2008
Defective cell cycle checkpoint functions in melanoma are associated with altered patterns of gene expression.
The Journal of investigative dermatology
Kaufmann WK,Nevis KR,Qu P,Ibrahim JG,Zhou T,Zhou Y,Simpson DA,Helms-Deaton J,Cordeiro-Stone M,Moore DT,Thomas NE,Hao H,Liu Z,Shields JM,Scott GA,Sharpless NE
MA5-14353 was used in western blot to study whether global patterns of gene expression can predict the efficacy of DNA damage cell cycle checkpoints in melanoma
Tue Jan 01 00:00:00 EST 2008
MDMX promotes proteasomal turnover of p21 at G1 and early S phases independently of, but in cooperation with, MDM2.
Molecular and cellular biology
Jin Y,Zeng SX,Sun XX,Lee H,Blattner C,Xiao Z,Lu H
MA5-14353 was used in immunoprecipitation and western blot to investigate the regulatory effect of MDMX on p21 during the cell cycle
Fri Feb 01 00:00:00 EST 2008
MDMX promotes proteasomal turnover of p21 at G1 and early S phases independently of, but in cooperation with, MDM2.
Molecular and cellular biology
Jin Y,Zeng SX,Sun XX,Lee H,Blattner C,Xiao Z,Lu H
MA5-14353 was used in immunoprecipitation and western blot to investigate the regulatory effect of MDMX on p21 during the cell cycle
Fri Feb 01 00:00:00 EST 2008
Aberrant expression of nucleostemin activates p53 and induces cell cycle arrest via inhibition of MDM2.
Molecular and cellular biology
Dai MS,Sun XX,Lu H
MA5-14353 was used in western blot to study the mechanism by which aberrant expression of nucleostemin iinduces cell cycle arrest
Tue Jul 01 00:00:00 EDT 2008
A 39 kDa fragment of endogenous ASK1 suggests specific cleavage not degradation by the proteasome.
IUBMB life
Stordal B,Davey R
MA5-14353 was used in western blot to investigate the different proteolytic cleavage between transfected ASK1 and endogenous ASK1
Sat Mar 01 00:00:00 EST 2008
Involvement of the role of Chk1 in lithium-induced G2/M phase cell cycle arrest in hepatocellular carcinoma cells.
Journal of cellular biochemistry
Wang XM,Li J,Feng XC,Wang Q,Guan DY,Shen ZH
MA5-14353 was used in western blot to study the mechanism by which lithium induces cell cycle arrest in hepatocellular carcinoma cells
Tue Jul 01 00:00:00 EDT 2008
Defining targets of modulation of human tumor cell response to cisplatin.
Journal of inorganic biochemistry
Beretta GL,Gatti L,Corna E,Carenini N,Zunino F,Perego P
MA5-14353 was used in western blot to study whether genes involved in the yeast drug response were modulated by cisplatin in human tumor cell lines
Tue Jul 01 00:00:00 EDT 2008
Oligomeric proanthocyanidin complexes (OPC) exert anti-proliferative and pro-apoptotic effects on prostate cancer cells.
The Prostate
Neuwirt H,Arias MC,Puhr M,Hobisch A,Culig Z
MA5-14353 was used in western blot to study the anti-proliferative and pro-apoptotic effects of oligomeric proanthocyanidin complexes on prostate cancer cells
Sat Nov 01 00:00:00 EDT 2008
hTERT expression in colorectal adenocarcinoma: correlations with p21, p53 expressions and clinicopathological features.
International journal of colorectal disease
Lam AK,Ong K,Ho YH
MA5-14353 was used in immunohistochemistry to investigate the expression of hTERT in colorectal adenocarcinoma and its correlation with p21 and p53
Sun Jun 01 00:00:00 EDT 2008
Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells.
Molecular cell
Larochelle S,Merrick KA,Terret ME,Wohlbold L,Barboza NM,Zhang C,Shokat KM,Jallepalli PV,Fisher RP
MA5-14353 was used in western blot to study the role of Cdk7 in assembly of Cdk1/cyclin B and activation of Cdk2 in human cells using chemical genetics
Fri Mar 23 00:00:00 EDT 2007
Induction of cullin 7 by DNA damage attenuates p53 function.
Proceedings of the National Academy of Sciences of the United States of America
Jung P,Verdoodt B,Bailey A,Yates JR,Menssen A,Hermeking H
MA5-14353 was used in western blot to study the role of cullin 7 in the attenuation of p53 function by DNA danage
Tue Jul 03 00:00:00 EDT 2007
Histone deacetylase inhibitors induce the degradation of the t(8;21) fusion oncoprotein.
Oncogene
Yang G,Thompson MA,Brandt SJ,Hiebert SW
MA5-14353 was used in western blot to study degradation of the t(8;21) fusion oncoprotein induced by histone deacetylase inhibitors
Thu Jan 04 00:00:00 EST 2007
Antitumor activity of CTFB, a novel anticancer agent, is associated with the down-regulation of nuclear factor-kappaB expression and proteasome activation in head and neck squamous carcinoma cell lines.
Molecular cancer therapeutics
Skvortsov S,Skvortsova I,Stasyk T,Schiefermeier N,Neher A,Gunkel AR,Bonn GK,Huber LA,Lukas P,Pleiman CM,Zwierzina H
MA5-14353 was used in western blot to investigate the mechanism for the antitumor activity of 5-Chloro-N-[2-[2-(4-chloro-phenyl)-3-methyl-butoxy]-5-trifluoromethyl-phenyl]-2-hydroxy-benzamide in head and neck cancer cell lines
Fri Jun 01 00:00:00 EDT 2007
AZD6244 and doxorubicin induce growth suppression and apoptosis in mouse models of hepatocellular carcinoma.
Molecular cancer therapeutics
Huynh H,Chow PK,Soo KC
MA5-14353 was used in western blot to study the ability of a mitogen-activated protein/ERK kinase 1/2 inhibitor and doxorubicin to suppress growth and promote apoptosis inhepatocellular carcinoma
Sat Sep 01 00:00:00 EDT 2007
D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation.
Molecular cancer therapeutics
Juang SH,Lung CC,Hsu PC,Hsu KS,Li YC,Hong PC,Shiah HS,Kuo CC,Huang CW,Wang YC,Huang L,Chen TS,Chen SF,Fu KC,Hsu CL,Lin MJ,Chang CJ,Ashendel CL,Chan TC,Chou KM,Chang JY
MA5-14353 was used in western blot to study the mechanism of action of a novel selenophene-based triheterocycle derivative with potent antitumor activity
Mon Jan 01 00:00:00 EST 2007
p53-Dependent but ATM-independent inhibition of DNA synthesis and G2 arrest in cadmium-treated human fibroblasts.
Toxicology and applied pharmacology
Cao F,Zhou T,Simpson D,Zhou Y,Boyer J,Chen B,Jin T,Cordeiro-Stone M,Kaufmann W
MA5-14353 was used in western blot to study the roles of p53 and ATM in DNA synthesis and G2 arrest in cadmium-treated human fibroblasts
Mon Jan 15 00:00:00 EST 2007
Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.
The Journal of pharmacology and experimental therapeutics
Wiseman DA,Werner SR,Crowell PL
MA5-14353 was used in western blot to study the role of p21(Cip1) and p27(Kip1) in the induction of cell cycle arrest in human panceatic adenocarcinoma cells by isoprenoids
Thu Mar 01 00:00:00 EST 2007
Influence of glutathione on the induction of chromosome aberrations, delay in cell cycle kinetics and cell cycle regulator proteins in irradiated mouse bone marrow cells.
International journal of radiation biology
Ray S,Chatterjee A
MA5-14353 was used in western blot to investigate the effect of glutathione on chromosome aberrations, cell cycle kinetics, and cell cycle regulator proteins
Tue May 01 00:00:00 EDT 2007
Role of microphthalmia transcription factor (Mitf) in melanoma differentiation.
Biochemical and biophysical research communications
Lekmine F,Chang CK,Sethakorn N,Das Gupta TK,Salti GI
MA5-14353 was used in western blot to investigate the involvement of microphthalmia transcription factor in melanoma differentiation
Fri Mar 16 00:00:00 EDT 2007
Overexpressed TP73 induces apoptosis in medulloblastoma.
BMC cancer
Castellino RC,De Bortoli M,Lin LL,Skapura DG,Rajan JA,Adesina AM,Perlaky L,Irwin MS,Kim JY
MA5-14353 was used in western blot to investigate the apoptosis induced by the overexpression of TP73 in medulloblastoma
Thu Jul 12 00:00:00 EDT 2007
Inducible microRNA expression by an all-in-one episomal vector system.
Nucleic acids research
Epanchintsev A,Jung P,Menssen A,Hermeking H
MA5-14353 was used in western blot to develop an all-in-one episomal vector system for the inducible expression of microRNA
Mon Dec 18 00:00:00 EST 2006
Coupling caspase cleavage and ubiquitin-proteasome-dependent degradation of SSRP1 during apoptosis.
Cell death and differentiation
Landais I,Lee H,Lu H
MA5-14353 was used in western blot to study the interaction between caspase cleavage and SSRP1 degradation during apoptosis
Wed Nov 01 00:00:00 EST 2006
Prolonged exposure to arecoline arrested human KB epithelial cell growth: regulatory mechanisms of cell cycle and apoptosis.
Toxicology
Lee PH,Chang MC,Chang WH,Wang TM,Wang YJ,Hahn LJ,Ho YS,Lin CY,Jeng JH
MA5-14353 was used in western blot to study the molecular mechanisms by which sustained exposure to arecoline blocks the growth of human KB epithelial cells
Wed Mar 15 00:00:00 EST 2006
N-all-trans-retinoyl-L-proline inhibits metastatic potential of hepatocellular carcinoma cells.
Cell biology international
Wu XZ,Shi PC,Hu P,Chen Y,Ding SS
MA5-14353 was used in western blot to examine the therapeutic effect of N-all-trans-retinoyl-L-proline in the metastasis of hepatocellular carcinoma cells
Tue Aug 01 00:00:00 EDT 2006
UV Induces p21 rapid turnover independently of ubiquitin and Skp2.
The Journal of biological chemistry
Lee H,Zeng SX,Lu H
MA5-14353 was used in western blot to investigate the impact of UV on p21 protein and its mechanism
Fri Sep 15 00:00:00 EDT 2006
Replication-dependent DNA damage response triggered by roscovitine induces an uncoupling of DNA replication proteins.
Cell cycle (Georgetown, Tex.)
Savio M,Cerri M,Cazzalini O,Perucca P,Stivala LA,Pichierri P,Franchitto A,Meijer L,Prosperi E
MA5-14353 was used in western blot to study the effects of the Cdk inhibitor roscovitine on DNA replication proteins
Fri Sep 01 00:00:00 EDT 2006
Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells.
World journal of gastroenterology
Wu XZ,Zhang L,Shi BZ,Hu P
MA5-14353 was used in flow cytometry, flow cytometry, immunocytochemistry, immunocytochemistry, western blot, and western blot to investigate the inhibitory effect of N-(4-hydrophenyl) retinamide on hepatocellular carcinoma cells and malignant melanoma
Fri Oct 07 00:00:00 EDT 2005
Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells.
World journal of gastroenterology
Wu XZ,Zhang L,Shi BZ,Hu P
MA5-14353 was used in flow cytometry, flow cytometry, immunocytochemistry, immunocytochemistry, western blot, and western blot to investigate the inhibitory effect of N-(4-hydrophenyl) retinamide on hepatocellular carcinoma cells and malignant melanoma
Fri Oct 07 00:00:00 EDT 2005
Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells.
World journal of gastroenterology
Wu XZ,Zhang L,Shi BZ,Hu P
MA5-14353 was used in flow cytometry, flow cytometry, immunocytochemistry, immunocytochemistry, western blot, and western blot to investigate the inhibitory effect of N-(4-hydrophenyl) retinamide on hepatocellular carcinoma cells and malignant melanoma
Fri Oct 07 00:00:00 EDT 2005
Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells.
World journal of gastroenterology
Wu XZ,Zhang L,Shi BZ,Hu P
MA5-14353 was used in flow cytometry, flow cytometry, immunocytochemistry, immunocytochemistry, western blot, and western blot to investigate the inhibitory effect of N-(4-hydrophenyl) retinamide on hepatocellular carcinoma cells and malignant melanoma
Fri Oct 07 00:00:00 EDT 2005
Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells.
World journal of gastroenterology
Wu XZ,Zhang L,Shi BZ,Hu P
MA5-14353 was used in flow cytometry, flow cytometry, immunocytochemistry, immunocytochemistry, western blot, and western blot to investigate the inhibitory effect of N-(4-hydrophenyl) retinamide on hepatocellular carcinoma cells and malignant melanoma
Fri Oct 07 00:00:00 EDT 2005
Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells.
World journal of gastroenterology
Wu XZ,Zhang L,Shi BZ,Hu P
MA5-14353 was used in flow cytometry, flow cytometry, immunocytochemistry, immunocytochemistry, western blot, and western blot to investigate the inhibitory effect of N-(4-hydrophenyl) retinamide on hepatocellular carcinoma cells and malignant melanoma
Fri Oct 07 00:00:00 EDT 2005
The chemoprotective agent N-acetylcysteine blocks cisplatin-induced apoptosis through caspase signaling pathway.
The Journal of pharmacology and experimental therapeutics
Wu YJ,Muldoon LL,Neuwelt EA
MA5-14353 was used in western blot to study the mechanism by which N-acetylcysteine blocks apoptosis and cytotoxicity induced by cisplatin treatment
Tue Feb 01 00:00:00 EST 2005
Xrcc3 induces cisplatin resistance by stimulation of Rad51-related recombinational repair, S-phase checkpoint activation, and reduced apoptosis.
The Journal of pharmacology and experimental therapeutics
Xu ZY,Loignon M,Han FY,Panasci L,Aloyz R
MA5-14353 was used in western blot to study the mechanism by which Xrcc3 induces cisplatin resistance
Mon Aug 01 00:00:00 EDT 2005
A mechanistic basis for the role of cycle arrest in the genetic toxicology of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Toxicological sciences : an official journal of the Society of Toxicology
Creton S,Zhu H,Gooderham NJ
MA5-14353 was used in western blot to study the role of cycle arrest in the genetic toxicology of a food carcinogen
Fri Apr 01 00:00:00 EST 2005
The mitogen-activated protein kinase kinase kinase dual leucine zipper-bearing kinase (DLK) acts as a key regulator of keratinocyte terminal differentiation.
The Journal of biological chemistry
Robitaille H,Proulx R,Robitaille K,Blouin R,Germain L
MA5-14353 was used in western blot to study the role of the MAP kinase kinase kinase dual leucine zipper-bearing kinase in regulating keratinocyte terminal differentiation
Fri Apr 01 00:00:00 EST 2005
Cell-type-specific responses to chemotherapeutics in breast cancer.
Cancer research
Troester MA,Hoadley KA,Sørlie T,Herbert BS,Børresen-Dale AL,Lønning PE,Shay JW,Kaufmann WK,Perou CM
MA5-14353 was used in western blot to study cell-type-specific responses to chemotherapeutics in breast cancer
Tue Jun 15 00:00:00 EDT 2004
Role for BRG1 in cell cycle control and tumor suppression.
Molecular and cellular biology
Hendricks KB,Shanahan F,Lees E
MA5-14353 was used in immunoprecipitation and western blot to study the role of BRG1 in the regulation of the cell cycle and tumor growth
Thu Jan 01 00:00:00 EST 2004
Role for BRG1 in cell cycle control and tumor suppression.
Molecular and cellular biology
Hendricks KB,Shanahan F,Lees E
MA5-14353 was used in immunoprecipitation and western blot to study the role of BRG1 in the regulation of the cell cycle and tumor growth
Thu Jan 01 00:00:00 EST 2004
Functional and physical interaction of the human ARF tumor suppressor with Tat-binding protein-1.
The Journal of biological chemistry
Pollice A,Nasti V,Ronca R,Vivo M,Lo Iacono M,Calogero R,Calabrò V,La Mantia G
MA5-14353 was used in western blot to study the interaction of the human ARF tumor suppressor with Tat-binding protein-1
Fri Feb 20 00:00:00 EST 2004
MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation.
The EMBO journal
Jin Y,Lee H,Zeng SX,Dai MS,Lu H
MA5-14353 was used in immunocytochemistry, western blot, and western blot to investigate the effect of MDM2 on p21waf1/cip1 function.
Mon Dec 01 00:00:00 EST 2003
MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation.
The EMBO journal
Jin Y,Lee H,Zeng SX,Dai MS,Lu H
MA5-14353 was used in immunocytochemistry, western blot, and western blot to investigate the effect of MDM2 on p21waf1/cip1 function.
Mon Dec 01 00:00:00 EST 2003
MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation.
The EMBO journal
Jin Y,Lee H,Zeng SX,Dai MS,Lu H
MA5-14353 was used in immunocytochemistry, western blot, and western blot to investigate the effect of MDM2 on p21waf1/cip1 function.
Mon Dec 01 00:00:00 EST 2003
Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array.
Cancer research
Dong Y,Zhang H,Hawthorn L,Ganther HE,Ip C
MA5-14353 was used in western blot to study the mechanism underlying the growth arrest of human prostate cancer cells induced by selenium
Wed Jan 01 00:00:00 EST 2003
S100C/A11 is a key mediator of Ca(2+)-induced growth inhibition of human epidermal keratinocytes.
The Journal of cell biology
Sakaguchi M,Miyazaki M,Takaishi M,Sakaguchi Y,Makino E,Kataoka N,Yamada H,Namba M,Huh NH
MA5-14353 was used in western blot to study the role of S100C/A11 as a key mediator of Ca(2+)-induced growth inhibition of human epidermal keratinocytes
Mon Nov 24 00:00:00 EST 2003
P27Kip1 and p21Cip1 are not required for the formation of active D cyclin-cdk4 complexes.
Molecular and cellular biology
Bagui TK,Mohapatra S,Haura E,Pledger WJ
MA5-14353 was used in immunoprecipitation and western blot to study the involvement of p27Kip1 and p21Cip1 in the formation of active D cyclin-cdk4 complexes
Wed Oct 01 00:00:00 EDT 2003
P27Kip1 and p21Cip1 are not required for the formation of active D cyclin-cdk4 complexes.
Molecular and cellular biology
Bagui TK,Mohapatra S,Haura E,Pledger WJ
MA5-14353 was used in immunoprecipitation and western blot to study the involvement of p27Kip1 and p21Cip1 in the formation of active D cyclin-cdk4 complexes
Wed Oct 01 00:00:00 EDT 2003
Mammary epithelial cells of PR-A transgenic mice exhibit distinct alterations in gene expression and growth potential associated with transformation.
Carcinogenesis
Chou YC,Uehara N,Lowry JR,Shyamala G
MA5-14353 was used in immunohistochemistry and western blot to investigate growth potential and gene expression of mammary epithelial cells derived from progesterone receptor A transgenic mice
Sat Mar 01 00:00:00 EST 2003
Mammary epithelial cells of PR-A transgenic mice exhibit distinct alterations in gene expression and growth potential associated with transformation.
Carcinogenesis
Chou YC,Uehara N,Lowry JR,Shyamala G
MA5-14353 was used in immunohistochemistry and western blot to investigate growth potential and gene expression of mammary epithelial cells derived from progesterone receptor A transgenic mice
Sat Mar 01 00:00:00 EST 2003
Caffeine and human DNA metabolism: the magic and the mystery.
Mutation research
Kaufmann WK,Heffernan TP,Beaulieu LM,Doherty S,Frank AR,Zhou Y,Bryant MF,Zhou T,Luche DD,Nikolaishvili-Feinberg N,Simpson DA,Cordeiro-Stone M
MA5-14353 was used in western blot to study the effects of caffeine on cell cycle checkpoint function and genotoxicity in telomerase-expressing human fibroblasts following DNA damage
Thu Nov 27 00:00:00 EST 2003
E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression.
Cell
Chen CR,Kang Y,Siegel PM,Massagué J
MA5-14353 was used in western blot to study the role of E2F4/5, p107 and Smad in TGFbeta receptor-mediated c-myc repression
Fri Jul 12 00:00:00 EDT 2002
G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells.
The Journal of clinical investigation
Blajeski AL,Phan VA,Kottke TJ,Kaufmann SH
MA5-14353 was used in western blot to study the effect of microtubule-destabilizing agents on cell-cycle arrest in human breast cancer cells
Mon Jul 01 00:00:00 EDT 2002
Notch signaling induces cell cycle arrest in small cell lung cancer cells.
Cancer research
Sriuranpong V,Borges MW,Ravi RK,Arnold DR,Nelkin BD,Baylin SB,Ball DW
MA5-14353 was used in western blot to study the induction of cell cycle arrest in small cell lung cancer cells by Notch
Sun Apr 01 00:00:00 EST 2001
Differential roles of p21(Waf1) and p27(Kip1) in modulating chemosensitivity and their possible application in drug discovery studies.
Molecular pharmacology
Schmidt M,Lu Y,Parant JM,Lozano G,Bacher G,Beckers T,Fan Z
MA5-14353 was used in western blot to study the modulation of chemosensitivity by p21(Waf1) and p27(Kip1) and the significance for drug discovery efforts
Thu Nov 01 00:00:00 EST 2001
Comparison of potential markers of farnesyltransferase inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research
Adjei AA,Davis JN,Erlichman C,Svingen PA,Kaufmann SH
MA5-14353 was used in western blot to evaluate potential markers of farnesyltransferase inhibition by peptidomimetic and non-peptidomimetic inhibitors
Thu Jun 01 00:00:00 EDT 2000