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PA5-16902 targets Oct-2 in IHC (P) applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-16902 immunogen is synthetic peptide derived from C-terminus of human Oct-2.
OCT-2 is a transcription factor belonging to the POU homeo-domain family that binds to the Ig gene octamer sites regulating B cell specific genes. OCT-2 protein expression is not restricted to B cells, although expression levels are much higher in these cells. OCT-2 expression is reported to be significantly greater in germinal center derived lymphomas, although other B cell lymphomas also display high levels of expression.
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