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          System Message

          OKCancel
          LOADING ...
          See other PTPN1 SIRNA Assays ›
          Gene Symbol:
          Ptpn1
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 1
          Gene Aliases:
          PTP-1B, PTP-HA2, PTP1B
          Chromosome Location:
          Chr.2: 167932303 - 167979385 on Build GRCm38
          UniGene ID:
          Mm.277916
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 68792

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Ptpn1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_011201.3 NP_035331.3 3 358
          GenBank mRNA AK149979.1 - 3 314
          AK150322.1 - 3 314
          AK151371.1 - 3 271
          AK153088.1 - 3 297
          AK156281.1 - 3 319
          AK157431.1 - 3 359
          AK165949.1 - 4 438
          AK166020.1 - 3 314
          AK168255.1 - 3 296
          AK168772.1 - 3 313
          AK170620.1 - 3 314
          AK171380.1 - 3 314
          AK172206.1 - 4 431
          AK185938.1 - 2 65
          BC010191.1 - 3 276 3156854
          M97590.1 - 3 274

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_012637, XM_006235638, XM_006235639, BC081829, M33962.

          Panther Classification:

          Molecular Function -

          protein phosphatase

          Gene Ontology Categories:

          Function(s) Process(es)

          protein dephosphorylation
          activation of JUN kinase activity
          insulin receptor signaling pathway
          regulation of signal transduction
          dephosphorylation
          regulation of endocytosis
          negative regulation of vascular endothelial growth factor receptor signaling pathway
          endoplasmic reticulum unfolded protein response
          actin cytoskeleton reorganization
          regulation of intracellular protein transport
          response to endoplasmic reticulum stress
          peptidyl-tyrosine dephosphorylation
          platelet-derived growth factor receptor-beta signaling pathway
          IRE1-mediated unfolded protein response
          negative regulation of MAP kinase activity
          regulation of insulin receptor signaling pathway
          positive regulation of protein tyrosine kinase activity
          negative regulation of ERK1 and ERK2 cascade
          regulation of hepatocyte growth factor receptor signaling pathway
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
          negative regulation of PERK-mediated unfolded protein response
          peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
          positive regulation of receptor catabolic process
          phosphoprotein phosphatase activity
          protein tyrosine phosphatase activity
          insulin receptor binding
          zinc ion binding
          hydrolase activity
          phosphatase activity
          enzyme binding
          protein kinase binding
          receptor tyrosine kinase binding
          poly(A) RNA binding
          ephrin receptor binding
          protein phosphatase 2A binding

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          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
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