Shop All Nucleic Acid Purification Systems

KingFisher™ Flex Purification System Thermo Scientific™

Prepare samples efficiently from a variety of materials with Thermo Scientific™ KingFisher™ Flex Purification Systems, which offers highly versatile, automated magnetic-particle processing for DNA/RNA, protein or cell purification from virtually any source. Using revolutionary magnetic particle separation technology, this system provides excellent reproduciblity and quality.

Hydroshear DNA Shearing Device (115 V) Applied Biosystems™

The Hydroshear® is a reproducible and controllable method for generating random DNA fragments of specific sizes used for mate-paired library preparations in the SOLiD™ System and 5500 series Genetic Analyzers. This instument includes the Hydroshear® for use with 115V.

For Research Use Only. Not for use in diagnostics procedures.

KingFisher™ Flex Purification System, KingFisher with 96 Deep-well Head Thermo Scientific™

Prepare samples efficiently from a variety of materials with the Thermo Scientific™ KingFisher™ Flex Purification System, which offers highly versatile, automated magnetic-particle processing for DNA/RNA, protein or cell purification from virtually any source. Using revolutionary magnetic particle separation technology, this system provides excellent reproduciblity and quality.

Hydroshear DNA Shearing Device (230 V) Applied Biosystems™

The Hydroshear® is a reproducible and controllable method for generating random DNA fragments of specific sizes used for mate-paired library preparations in the SOLiD™ System and 5500 series Genetic Analyzers. This instument includes the Hydroshear® for use with 230V.

For Research Use Only. Not for use in diagnostics procedures.

Pharma KingFisher™ Flex 96 Deep-Well Magnetic Particle Processor Applied Biosystems™

The Thermo Scientific™ Pharma KingFisher™ Flex 96 Deep-well Head Magnetic Particle Processor is intended for pharmaceutical analytics applications and is an excellent option for facilities that wish to automate their PrepSEQ™ Residual DNA or PrepSEQ™ 1-2-3 nucleic acid extraction kit protocols. The KingFisher Flex platform is a premier automated platform designed to meet your high-throughput needs. It seamlessly incorporates the rapid, reliable, and cost-effective magnetic bead-based extraction of nucleic acids that you expect from PrepSEQ technology with a 96-well automation system. Using magnetic particle separation technology, this system provides excellent reproducibility and quality.

Key product features:
• Reliable recovery—quantitative and consistent nucleic acid recovery and cross-contamination control
• Efficient isolation—high-quality and high-throughput isolation of nucleic acids from Mycoplasma, Vesivirus, MMV, and residual DNA
• Streamlined design—superior performance and cost effectiveness per reaction
• Modular & versatile application—fully compatible with the PrepSEQ nucleic acid extraction kits

Quantitative & consistent recovery
Quantitative and consistent recovery of DNA from challenging matrices—including samples that have high protein concentration, low pH, or high salt—often presents a technical challenge. The PrepSEQ nucleic acid extraction kits are now adapted for higher-throughput workflows (up to 96 extractions, or 24 samples in triplicate) when used in combination with the KingFisher Flex 96 Deep-well Head Magnetic Particle Processor. The special formulation of magnetic particles provided in the PrepSEQ kits help ensure efficient and specific recovery of DNA from challenging samples.

High quality & throughput isolation
Most automated liquid handling systems move reagents into and out of a single well to perform the different steps of nucleic acid isolation. In contrast, the KingFisher Flex 96 Deep-well Head Magnetic Particle Processor utilizes permanent rods to collect the magnetic beads from solution and releases the beads into a well containing reagents for the next step of isolation. The effectiveness of bead collection and transfer leads to superior washing, elution efficiency, and processing. The KingFisher Flex 96 Deep-well Head Magnetic Particle Processor can process up to 24 samples in triplicate, compared to 3 samples in triplicate using the manual method.

Compatible with PrepSEQ sample preparation kits
The KingFisher Flex 96 Deep-well Head Magnetic Particle Processor has been optimized to work with both the PrepSEQ Residual DNA Sample Preparation Kit and the PrepSEQ 1-2-3 Nucleic Acid Extraction Kit assays. The instrument comes pre-installed with PrepSEQ optimized protocols and does not require any further optimization after installation and validation.

KingFisher Apex Benchtop Sample Prep Thermo Scientific™

KingFisher Apex is a versatile and user-friendly instrument which uses magnetic particle processing to automate the purification or isolation of DNA, RNA, proteins, and cells from virtually any source. The Apex moves magnetic beads not liquids through the main steps of sample preparation -- bind, wash, elute. This process provides excellent quality, reproducible results, and reduces hands-on time for sample processing. 

KingFisher™ Duo Prime Purification System Thermo Scientific™

Reap high yields of quality nucleic acids from a variety of starting materials with the Thermo Scientific™ KingFisher™ Duo Prime purification system. This compact instrument is ideal for laboratories requiring nucleic acid purification, and is easily modified for use in proteomics and cell isolation. It provides excellent reproducibility with minimal hands-on time, and has a small footprint in the lab. New features, including a UV lamp for easy decontamination and optional bar-code reader enhance functionality.

KingFisher™ Purification System Thermo Scientific™

Automate time-consuming sample preparation processes of nucleic acids, proteins and cells from virtually any source with Thermo Scientific™ KingFisher™ Purification Systems. With the ability to purify small-scale samples using magnetic particle processing, these high-quality machines carry out all purification steps in microplates with simple push-button operation; up to 24 samples can be processed per run.

KingFisher™ Presto Purification System Thermo Scientific™

Use the Thermo Scientific™ KingFisher™ Presto as part of an automated purification system with a liquid handler for plate filling in high-throughput laboratories. Utilizing proven KingFisher magnetic particle-based technology, the KingFisher Presto provides high-quality yields of target nucleic acids and proteins for biopharma, biotech and research.

KingFisher™ Flex Purification System, KingFisher with 24 Deep-well Head Thermo Scientific™

Prepare samples efficiently from a variety of materials with the Thermo Scientific™ KingFisher™ Flex Purification System, which offers highly versatile, automated magnetic-particle processing for DNA/RNA, protein or cell purification from virtually any source. Using revolutionary magnetic particle separation technology, this system provides excellent reproduciblity and quality.

Ultra-Turrax Tube Drive from IKA™ Applied Biosystems™

The ULTRA-TURRAX® Tube Drive from IKA® is a sample preparation instrument for use in the SOLiD™ System workflow. This instrument is required for the preparation of consistently sized reactors for emulsion PCR.

KingFisher™ Cell and Tissue DNA Kit Thermo Scientific™

Rapidly purify high-quality, reproducible DNA from cell and tissue samples, as well as cultured bacteria, with the Thermo Scientific™ KingFisher™ Cell and Tissue DNA Kit. This unique nucleic acid purification workflow provides an optimized, high-throughput method for extreme flexibility.

KingFisher™ Flex Purification System, KingFisher with 96 PCR head Thermo Scientific™

Prepare samples efficiently from a variety of materials with the Thermo Scientific™ KingFisher™ Flex Purification System, which offers highly versatile, automated magnetic-particle processing for DNA/RNA, protein or cell purification from virtually any source. Using revolutionary magnetic particle separation technology, this system provides excellent reproduciblity and quality.

KingFisher™ mL Purification System Thermo Scientific™

Automate low-throughput sample preparation within your laboratory workflow using Thermo Scientific™ KingFisher mL Purification System: optimized for extreme flexibility. The system-of-choice for processing volumes up to 1mL, these magnetic particle processors enable all purification steps in a single-strip of five tubes, and support 15 processed samples per run. With the ability to go down to 50μL to release target molecules, samples such as DNA or RNA can be isolated and concentrated from larger starting volumes simultaneously.

PrepSEQ™ Express Nucleic Acid Extraction Kit Applied Biosystems™

The AutoMate Express Nucleic Acid Extraction System is an easy-to-use benchtop instrument that enables hands-free automation of the nucleic acid extraction process for contaminant and impurity testing. The instrument uses the established PrepSEQ nucleic acid extraction chemistry for quantitative recovery of DNA and RNA from diverse samples types, including cell culture, raw material (e.g., serum), and in-process downstream purification samples such as column purification or bulk drug substance (BDS) samples.

Key features of the AutoMate Express Nucleic Acid Extraction System inlcude:
• Time-saving, cost-effective DNA extraction for mycoplasma, MMV, and vesivirus
• Reproducible recovery of DNA from complex samples
• Out-of-the-box automation with prefilled PrepSEQ Express cartridges and ready-to-run protocols
• Closed system minimizes the risk of contamination
• Ideal for in-process testing of contaminants

Three-in-one extraction of cell culture contaminants
The AutoMate Express system can be used to perform nucleic acid extraction of the common contaminants for mammalian cell culture manufacturing (mycoplasmas, MMV, and vesiviruses) (see figure below). Flexible protocols are available to isolate DNA and RNA from a single organism, or a 3-in-1 surveillance panel protocol can simultaneously extract mycoplasma, MMV, and vesivirus nucleic acid from a single sample.

Closed system with walk-away automation
The AutoMate Express system automatically performs all steps for efficient nucleic acid extraction from contaminants in a closed environment. The system uses PrepSEQ Express kits that contain sealed cartridges with extraction reagents and plastics, including tips and sample, lysis, and elution tubes. The workflow has been designed for a completely hands-free operation enabling reproducible extraction efficiencies and reduced time-to-results.

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