Starting with Serology: History and Evolution of HLA Assays. Back to Basics Series, Episode 5

Starting with Serology: History and Evolution of HLA Assays, Episode 5


This is the fifth episode of our foundational series, Back to Basics. It will cover early methods for studying HLA, how complement-dependent cytotoxicity (CDC) was used for multiple applications, and the development of increasingly sensitive immunologic and genetic assays for HLA. Technologies highlighted in our rapid tour through history include ELISA, solid-phase bead microarray assays, flow cytometry, SSP, SSO, SBT, and NGS. A key takeaway is the functional significance of earlier assays and how understanding them provides insight into the HLA system and current methodologies.
 

Instructor:
Linda Olsen, MPH, CHS(ACHI), MLS(ASCP)CM,

Sr. Technical Training Specialist – Molecular, Thermo Fisher Scientific

HLA Fundamentals: Back to Basics⠀⠀ ⠀⠀ ⠀⠀ ⠀

Meet the speaker

Linda serves as Technical Training Specialist for our molecular products, a role she has held since March 2022. She holds a bachelor’s degree in clinical laboratory science and a master’s in public health policy and management. She has worked in HLA since 2008, with experience at the University of Utah, Stanford, and ClinImmune Labs. Prior to joining the Technical Training team, she was supervisor of the HLA lab at Mayo Clinic Arizona. She has also served as an ASHI inspector and committee member. She enjoys teaching and increasing access to educational materials on the science and application of HLA.

More resources to aide you in your learning journey


These videos may contain general information relating to various medical conditions or their treatment. The information in this video is provided for informational purposes only and is not meant to be a substitute for advice provided by a doctor or other qualified health care professional. You should always consult with a doctor or other health care professional for medical advice or information about diagnosis and treatment.

Intended use of the products mentioned on this page vary. For specific intended use statements please refer to the product label.