Starting with Serology: History and Evolution of HLA Assays. Back to Basics Series, Episode 5

Starting with Serology: History and Evolution of HLA Assays, Episode 5


This is the fifth episode of our foundational series, Back to Basics. It will cover early methods for studying HLA, how complement-dependent cytotoxicity (CDC) was used for multiple applications, and the development of increasingly sensitive immunologic and genetic assays for HLA. Technologies highlighted in our rapid tour through history include ELISA, solid-phase bead microarray assays, flow cytometry, SSP, SSO, SBT, and NGS. A key takeaway is the functional significance of earlier assays and how understanding them provides insight into the HLA system and current methodologies.
 

Instructor:
Linda Olsen, MPH, CHS(ACHI), MLS(ASCP)CM,
Sr. Technical Training Specialist – Molecular, Thermo Fisher Scientific

HLA Fundamentals: Back to Basics⠀⠀ ⠀⠀ ⠀⠀ ⠀

Meet the speaker

Linda serves as Technical Training Specialist for our molecular products, a role she has held since March 2022. She holds a bachelor’s degree in clinical laboratory science and a master’s in public health policy and management. She has worked in HLA since 2008, with experience at the University of Utah, Stanford, and ClinImmune Labs. Prior to joining the Technical Training team, she was supervisor of the HLA lab at Mayo Clinic Arizona. She has also served as an ASHI inspector and committee member. She enjoys teaching and increasing access to educational materials on the science and application of HLA.

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