Polybrominated flame retardants, in particular polybrominated diphenyl ethers (PBDEs), are persistent organic compounds that are found in the environment and in the food chain. Biomonitoring data show that PBDE concentrations have increased in recent years—in humans and wildlife. Humans are exposed to PBDEs mainly through ingestion of contaminated food and breathing contaminated air. Since PBDEs are potentially linked to a wide range of adverse health effects in humans such as endocrine disruption, neurodevelopmental toxicity, and cancer, there is increasing public health concern about these compounds. The webinar will discuss the use of an advanced electron ionization (AEI) triple-quadrupole GC–MS technique for the routine analysis of PBDEs. It will also discuss the challenges that laboratories face in terms of selectivity and sensitivity in complex sample matrices, sample throughput, and reducing the cost per sample.

Further information will be provided on the following topics:

Ultratrace quantification of PBDEs in food and feed (at low ppt levels) levels using a new AEI source with triple quadrupole GC-MS Rapid sample throughput with full separation of 27 native PBDEs in <11 minutes Robust determination of PBDEs in complex matrices using electron ionization rather than soft ionization techniques such as negative chemical ionization

About the presenters

Sean Panton, Analytical Chemist, FERA Science Ltd

Sean Panton, Analytical Chemist, FERA Science Ltd

Sean is an analytical chemist working in the Organic Environmental Contaminants team at FERA Science Ltd, in York, UK. Sean has over 25 years of experience in food analysis. Sean started out in the pesticides team at FERA, developing GC and HPLC based methods and researching the fate of pesticides during food processing. For the last 15 years he has been involved in analysis of polyaromatic hydrocarbons (PAHs), PCBs, dioxins, brominated flame retardants (BFRs) in food and environmental samples using GC–MS, GC–MS/MS and GC–HRMS platforms.

Aaron Lamb, Senior Mass Spectrometry Applications Specialist, Thermo Fisher Scientific

Aaron Lamb, Senior Mass Spectrometry Applications Specialist, Thermo Fisher Scientific

Aaron is a senior mass spectrometry applications specialist working in the Chromatography and Mass Spectrometry Division at Thermo Fisher Scientific in Runcorn, UK. Aaron is an experienced analytical chemist and mass spectrometrist responsible for application method development using GC–MS, in particular using single- and triple quadrupole-based mass spectrometry for food and environmental markets. Aaron has also worked in industry as an R&D and Pharma Team Leader at Intertek using a multitude of analytical techniques including ion chromatography, GC–MS and LC–MS in health care and pharmaceutical analyses.

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