Rapid Separation (RS) HPLC Systems

Fast separations, high resolution, freedom of choice

Perform the full range of rapid HPLC and UHPLC applications on one system. Thermo Scientific UltiMate 3000 Rapid Separation systems combine unique hardware features and the ability to use small particle columns for fast separations with excellent resolution. All system components are coordinated for high performance. Available in biocompatible and non-biocompatible setups and featuring unique technological innovations like dual-gradient capabilities, the UltiMate 3000 RS systems sustain even most advanced workflows.

Browse our complete portfolio below, or let one of our experts help you tailor a selection specific to your application and workflow needs.

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Rapid separation HPLC systems

Rapid Separation (RS) Systems
Rapid Separation (RS) Systems

Providing ultra-fast separations with ultra-high resolution in an exceptionally versatile HPLC/UHPLC system for the rigorous demands of large and small molecule analysis, these systems operate at pressures up to 1000 bar.

UltiMate 3000 Rapid Separation Binary SystemGet fast, high resolution separations with maximum flow rate flexibility. A fast gradient response and excellent flow rate stability ensure reliable results.
UltiMate 3000 Rapid Separation Quaternary SystemThis is the most flexible RS system for established and novel HPLC and UHPLC workflows. The quaternary system supports fast routine applications and method development.
UltiMate 3000 Rapid Separation Dual SystemIncrease productivity with this dual rapid separation system featuring online-SPE, parallel or tandem HPLC/UHPLC, inverse gradients and fast application switching.
Biocompatible Rapid Separation (BioRS) Systems
Biocompatible Rapid Separation (BioRS) Systems

Get UHPLC performance for proteins, peptides, nucleic acids, and biotherapeutics. These systems are 100% corrosion free for use with high salt or extreme pH conditions. They operate with column pressures up to 1000 bar.

UltiMate 3000 BioRS SystemProtect your large molecules from unwanted degradation and modification. This UHPLC handles your needs from discovery to target isolation and purification.
UltiMate 3000 BioRS Dual SystemAccelerate your Bio-UHPLC analyses. This dual system automates multiple UHPLC separations to combine non-compatible chemistries in one workflow.
Featured UltiMate 3000 BioRS system video
Quick overview of the UltiMate 3000 BioRS system

The UltiMate 3000 BioRS is designed to combine the performance advantages of ultra-high-performance liquid chromatography (UHPLC) with the corrosion-resistant flow path needed to analyze proteins, peptides, nucleic acids and biotherapeutics. The system was designed to accelerate research into promising biotherapies, such as monoclonal antibody variants.

Discover the best HPLC systems for your applications and budget

Discover the best HPLC system for your applications and budget

Use these tools to help you decide

HPLC Systems Selection Guide
Use this tool to rank the top HPLC instruments for your applications based on your responses to simple pull-down menus.

HPLC System Total Cost of Ownership Calculator
Use this tool to estimate your cost for purchasing and running Thermo Scientific HPLC and UHPLC systems. You can compare costs between instruments.

LC Method Transfer Calculator
Use this online calculator to transfer methods from HPLC to UHPLC conditions. Calculate the new gradient table, adjust sample volumes and run times if applicable.

Featured on-demand HPLC webinars
Featured on-demand HPLC webinars

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