Small Molecule Bioanalysis and DMPK Studies

Ensure sensitive, robust analysis for small molecule clinical drug trials

Understanding your molecules is critical, and ensuring accuracy throughout sample preparation, analysis and data interpretation is paramount when it comes to your DMPK studies. Regardless of matrix complexity, sample throughput or sensitivity and linearity requirements, find out what it takes to meet these challenges with ease – all in a 21 CFR Part 11 and GxP compliant environment.

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Popular small molecule bioanalysis products

Featured small molecule bioanalysis categories

Designed with innovative technology and fine detail, the Thermo Scientific Vanquish Horizon UHPLC System delivers a new standard in high-end UHPLC – more results with better separations and easier interaction simultaneously, without compromise.

For the most complex samples and the highest throughput, you can be sure that the Vanquish Horizon delivers the utmost confidence for your LC-MS quantitative workflows.

 Vanquish UHPLC brochure

Your samples are both precious and limited, the Thermo Scientific TSQ Altis Triple Quadrupole Mass Spectrometer ensures supreme quantitative performance without compromise.

Meet your analytical challenges and goals every day, for every sample with robust, sensitive and efficient targeted quantitation workflows.

 TSQ Altis brochure
 Application note: Quantitative analysis of drug candidates in plasma

Easily answer critical analytical challenges during targeted quantitation workflows in your laboratory. With the sensitivity and reproducibility to quantitate any molecule in complex biological matrices, the Thermo Scientific TSQ Quantis Triple Quadrupole Mass Spectrometer delivers – workflow driven solutions for absolute confidence.

 TSQ Quantis brochure

Thermo Scientific Chromeleon 7.2 Chromatography Data System software unifies workflows for chromatography and routine quantitative MS analysis, providing full integration of Thermo Scientific's gas chromatography (GC)-MS/MS and liquid chromatography (LC)-MS/MS instruments in a 21 CFR Part 11 and GxP compliant environment, as well as more than 400 other instruments from over 15 different vendors. Quickly and easily process and report UV and MS data in one application. Run your analyses in an enterprise environment – from method creation through to quantitation and library-based compound identification.

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Confident quantitation

Scientists are being challenged to develop quantitation workflows in complex matrices whilst reducing cost per sample, in addition to producing robust, reliable and reproducible solutions.

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