Scientist and digital resource icons

Knowledge illuminates the way forward

Welcome to the Chromatography Learning Lab, where you can find a dynamic and robust range of digital resources curated for your bioprocess chromatography needs. Here, you’ll discover a diverse collection of specialized knowledge and innovative solutions that can help you stay on the cutting edge.

Bioprocess Resin Selection Tool

Use this interactive decision-making tool to determine the right chromatography resin for your purification process.


Articles                        eBooks                        Posters                        Webinars

Articles

Monoclonal Antibody Aggregate Polish and Viral Clearance Using Hydrophobic-Interaction Chromatography

Gain insight on using HIC purification, including viral clearance data, for monoclonal antibodies requiring aggressive strategies for aggregate clearance.

Improving Aggregate Removal to Enhance Clinical Manufacturing of mAbs

Gain knowledge from this case study describing mAb aggregate removal using HIC in flow-through mode resulting in improved process efficiency and productivity, compared to a mixed-mode bind-elute step.

eBooks

Posters

Webinars

Innovation of Novel Purification Strategies: A Case Study of Clusterin Scavenger Resins

Learn about a scavenging clusterin, a common protein found in monoclonal antibody manufacturing, and topics such as the platform process for generating specific VHH antibody-based ligands

Novel Purification Approaches to Streamline Manufacturing of Antibody-Based Therapeutics

Discover our complete portfolio of innovative affinity capture and polish solutions to help you develop novel antibody molecules such as Fab fragments, Fc-fusion proteins, and bi-specific antibodies.

Articles          eBooks          Infographics          Posters          Webinars

Articles

Advancing the Purification of VSV-G Pseduotyped Lentiviral Vectors by Using Affinity Chromatography

Review the highlights of our discussion on an affinity resin that addresses the major challenges manufacturing processes for cell and gene therapy vectors derived from lentivirus.

Development of Purification Steps for Several AAV Serotypes Using POROS CaptureSelect AAVX Affinity Chromatography

Learn how a gene therapy company is testing POROS CaptureSelect AAVX affinity resin as a platform solution for the purification of various AAV vectors.

Platform Optimization for Efficient AAV Purification: Insights from a CDMO

Read and learn how POROS CaptureSelect AAVX resin can be used as a pan-affinity tool for the universal capture of AAV vectors and how a leading CDMO optimized the process of this resin to establish a robust purification platform.

Simplifying Lentiviral Downstream Processing with a Novel Affinity Resin and Robust Analytical Tools

Read and learn more about a new affinity chromatography resin to purify lentiviral particles and rapid analytical tools for titer determination and impurity quantification.

eBooks

Infographics

Posters

 

 

poster on the productivity optimization and process calculations for AAV affinity chromatography

 

Productivity Optimization and Process Calculations for AAV Affinity Chromatography

Find out how to leverage the dynamic binding capacity of a purification resin to address multiple AAV serotypes for bioprocess conditions for clinical and commercial scale manufacturing.

poster on the development of gene therapeutics using affinity resins

Accelerating Advancement in Gene Therapy Purification

Review this technical poster demonstrating the benefits of implementing affinity chromatography in the downstream purification of viral vectors.

Webinars

Platform Optimization for Efficient AAV Purification: Insights from a CDMO

Watch and learn how POROS CaptureSelect AAVX resin can be used as a pan-affinity tool for the universal capture of AAV vectors and how a leading CDMO optimized the process of this resin to establish a robust purification platform.

Articles             eBooks             Posters             Webinars

Articles

COVID-19 mRNA Vaccine Approvals: Key Lessons for Cell & Gene Therapy and mRNA Therapeutic Development

Read the conversation between thought-leaders from both the mRNA vaccine and therapeutics spheres as they share a unique cross-pollination of manufacturing experiences and ideas between both worlds.

eBooks

Infographic

Posters

Webinars

COVID-19 mRNA Vaccine Approvals: Key Lessons for Cell & Gene Therapy and mRNA Therapeutic Development

Listen to thought-leaders from both the mRNA vaccine and therapeutics spheres share a unique cross-pollination of manufacturing experiences and ideas between both worlds.

Articles                           Posters                        Webinars

Articles

Posters

Webinars

Articles               eBooks               Webinars

Articles

COVID-19 mRNA Vaccine Approvals: Key Lessons for Cell & Gene Therapy and mRNA Therapeutic Development

Read the conversation between thought-leaders from both the mRNA vaccine and therapeutics spheres as they share a unique cross-pollination of manufacturing experiences and ideas between both worlds.

Addressing Challenges Across the Virus Like Particle Workflow

Read to understand how an integrated system of tools for protein expression, affinity purification, and quality control testing can help support efficient and cost-effective virus like particle production on a commercial scale.

Purification and Quality Control Solutions to Accelerate Vaccine Development

Read to discover how novel chromatography solutions and analytical testing can help improve the downstream processes of different vaccine modalities such as mRNA, recombinant proteins and Virus Like Particles (VLPs).

eBooks

Webinars

COVID-19 mRNA Vaccine Approvals: Key Lessons for Cell & Gene Therapy and mRNA Therapeutic Development 

Watch a conversation between thought-leaders from both the mRNA vaccine and therapeutics spheres as they share a unique cross-pollination of manufacturing experiences and ideas between both worlds.

Improving and Intensifying Vaccine Purification by Implementing Affinity Chromatography 

Understand how affinity chromatography can aid vaccine development and manufacturing by improving purification of vaccine modalities such as mRNA and protein subunits.

Virus-Like Particle Production in Insect Cells Using Baculovirus Express System: Addressing Challenges Across the Workflow

Watch to understand how an integrated system of tools for protein expression, affinity purification, and quality control testing can help support efficient and cost-effective virus-like particle production on a commercial scale.

Rapid Vaccine Manufacturing for Clinical Trials—Insights from the Malaria Field

Watch to learn how the C-tag affinity tag system is applied as a standard purification process for candidate malaria vaccines to support efficient translation into clinical trials.

Advancing Vaccine Development with Novel Chromatography Solutions and State of the Art Quality Testing 

Watch to discover how novel chromatography solutions and analytical testing can help improve the downstream processes of different vaccine modalities such as mRNA, recombinant proteins, and Virus Like Particles (VLPs).

Accelerating Vaccine Development and Large-Scale Manufacturing with Advanced Purification Tools

Learn how novel purification solutions can help improve the downstream process of different vaccine modalities such as mRNA, recombinant proteins, and Virus Like Particles (VLPs). 

Articles           eBooks            Posters           Videos         Webinars

Articles

eBooks

Pure and Simple: Affinity Chromatography Solutions for Complex Biotherapeutic Manufacturing

Discover how using affinity purification can help improve biotherapeutic manufacturing of antibody-based therapeutics, mRNA and vaccines, viral vectors, and other novel therapeutics.

Posters

 

 

poster on An innovative approach to addressing high aggregate challenges in engineered monoclonal antibodies

 

 

An Innovative Approach to Addressing High Aggregate Changes in Engineered Monoclonal Antibodies

Explore the performance of a monoclonal antibody purification solution in high-aggregate conditions that support the cation exchange step and the anion exchange-based final polishing step

poster on antibody-based selectivity in biologics purification

Advantage of Antibody Based Selectivity in the Purification of Biologics

Get more insight into CaptureSelect technology and how it can help solve challenges in the purification of various biologics.

Videos

Webinars

Addressing Purification Challenges for Complex Therapeutics with Custom Chromatography Resins

Learn how our custom resin platform and novel affinity ligand technology enables the development of innovative purification resins, providing a solution for challenging downstream processes.

Understanding Viral Clearance During Anion Exchange Chromatography by Using a Novel Design of Experiment Approach

Understand the outcome of a study on viral clearance study during AEX chromatography to improve effectivity and rigor of viral clearance at this step.

Articles                        eBooks                        Posters                        Webinars

Articles

Monoclonal Antibody Aggregate Polish and Viral Clearance Using Hydrophobic-Interaction Chromatography

Gain insight on using HIC purification, including viral clearance data, for monoclonal antibodies requiring aggressive strategies for aggregate clearance.

Improving Aggregate Removal to Enhance Clinical Manufacturing of mAbs

Gain knowledge from this case study describing mAb aggregate removal using HIC in flow-through mode resulting in improved process efficiency and productivity, compared to a mixed-mode bind-elute step.

eBooks

Posters

Webinars

Innovation of Novel Purification Strategies: A Case Study of Clusterin Scavenger Resins

Learn about a scavenging clusterin, a common protein found in monoclonal antibody manufacturing, and topics such as the platform process for generating specific VHH antibody-based ligands

Novel Purification Approaches to Streamline Manufacturing of Antibody-Based Therapeutics

Discover our complete portfolio of innovative affinity capture and polish solutions to help you develop novel antibody molecules such as Fab fragments, Fc-fusion proteins, and bi-specific antibodies.

Articles          eBooks          Infographics          Posters          Webinars

Articles

Advancing the Purification of VSV-G Pseduotyped Lentiviral Vectors by Using Affinity Chromatography

Review the highlights of our discussion on an affinity resin that addresses the major challenges manufacturing processes for cell and gene therapy vectors derived from lentivirus.

Development of Purification Steps for Several AAV Serotypes Using POROS CaptureSelect AAVX Affinity Chromatography

Learn how a gene therapy company is testing POROS CaptureSelect AAVX affinity resin as a platform solution for the purification of various AAV vectors.

Platform Optimization for Efficient AAV Purification: Insights from a CDMO

Read and learn how POROS CaptureSelect AAVX resin can be used as a pan-affinity tool for the universal capture of AAV vectors and how a leading CDMO optimized the process of this resin to establish a robust purification platform.

Simplifying Lentiviral Downstream Processing with a Novel Affinity Resin and Robust Analytical Tools

Read and learn more about a new affinity chromatography resin to purify lentiviral particles and rapid analytical tools for titer determination and impurity quantification.

eBooks

Infographics

Posters

 

 

poster on the productivity optimization and process calculations for AAV affinity chromatography

 

Productivity Optimization and Process Calculations for AAV Affinity Chromatography

Find out how to leverage the dynamic binding capacity of a purification resin to address multiple AAV serotypes for bioprocess conditions for clinical and commercial scale manufacturing.

poster on the development of gene therapeutics using affinity resins

Accelerating Advancement in Gene Therapy Purification

Review this technical poster demonstrating the benefits of implementing affinity chromatography in the downstream purification of viral vectors.

Webinars

Platform Optimization for Efficient AAV Purification: Insights from a CDMO

Watch and learn how POROS CaptureSelect AAVX resin can be used as a pan-affinity tool for the universal capture of AAV vectors and how a leading CDMO optimized the process of this resin to establish a robust purification platform.

Articles             eBooks             Posters             Webinars

Articles

COVID-19 mRNA Vaccine Approvals: Key Lessons for Cell & Gene Therapy and mRNA Therapeutic Development

Read the conversation between thought-leaders from both the mRNA vaccine and therapeutics spheres as they share a unique cross-pollination of manufacturing experiences and ideas between both worlds.

eBooks

Infographic

Posters

Webinars

COVID-19 mRNA Vaccine Approvals: Key Lessons for Cell & Gene Therapy and mRNA Therapeutic Development

Listen to thought-leaders from both the mRNA vaccine and therapeutics spheres share a unique cross-pollination of manufacturing experiences and ideas between both worlds.