A pyramidal neuron from rat hippocampus was first exposed to Alzheimer’s ß-amyloid peptide and then to the excitatory amino acid glutamate.
A pyramidal neuron from rat hippocampus was first exposed to Alzheimer’s ß-amyloid peptide and then to the excitatory amino acid glutamate. Confocal laser-scanning microscopy imaging using the intracellular Ca2+ indicator fluo-3 (Cat. no. F1241, F1242, F14218, F14242, F23915) shows that ß-amyloid peptide destabilizes the neuron’s calcium homeostasis and increases its vulnerability to excitotoxicity. The image was contributed by Mark P. Mattson, Sanders-Brown Center on Aging, University of Kentucky.
REF-52 fibroblasts. Cyclic AMP Fluorosensor (FlCRhR) and fura-2 AM Go ›
Pseudocolored images of changes in intracellular free Ca2+ in AtT-20/D16v-F2 cells, monitored at 9 sec intervals with fluo-4, AM (F14201, F14202, F14217, F23917). Go ›
Live cell imaging with CellLight™ reagents. Go ›
Live cells transduced with Organelle Lights™ or Cellular Lights™ reagents. Go ›
P-Cadherin Antibody (14-2237-82) in WB Go ›
CD321 (F11R) Antibody (14-3219-82) in WB Go ›
Developing Drosophila embryo Go ›
Cytoskeleton of a mixed population of granule neurons and glial cells Go ›