CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
InvitrogenCD21 Monoclonal Antibody (HB5), FITC, eBioscience™ CD21 Monoclonal Antibody (HB5), FITC, eBioscience™
Cat # 11-0219-42
InvitrogenCD21 Monoclonal Antibody (HB5), PerCP-eFluor 710, eBioscience™ CD21 Monoclonal Antibody (HB5), PerCP-eFluor 710, eBioscience™
Cat # 46-0219-42
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.