Cytokeratin 3 Antibodies
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
65 kDa cytokeratin; CK-3; cytokeratin 3; Cytokeratin-3; K3; keratin 3, type II; Keratin, type II cytoskeletal 3; Keratin-3; Type-II keratin Kb3