The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine.
Alpha-neoendorphin; Beta-neoendorphin; Beta-neoendorphin-dynorphin; Big Dyn; Big dynorphin; Dyn-A17; Dyn-B; Dynorphin A(1-13); Dynorphin A(1-17); Dynorphin A(1-8); Dynorphin B; Dynorphin B(1-13); Dynorphin B-29; Leu-enkephalin; Leumorphin; MGC26418; neoendorphin-dynorphin-enkephalin prepropeptide; Preprodynorphin; preproenkephalin B; Proenkephalin-B; Rimorphin
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