Acts as a transcriptional repressor. Involved in recruitment of functional SIN3A complexes to DNA. Represses transcription at least in part through the activity of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA.
Pf1; PHD factor 1; PHD finger protein 12; PHD zinc finger transcription factor; PHF12; PHF12 (HGNC:20816)