Anti-BUBR1 Antibodies

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BUBR1 Antibodies

Antibodies that detect BUBR1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target BUBR1 in Human, Mouse, Rat and Canine samples. Our BUBR1 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Sheep. These antibodies have been verified by Relative Expression to confirm specificity to BUBR1. Find the BUBR1 antibody that fits your needs. Choose from 1 of 53 BUBR1 antibodies, which have been validated in experiments with 6 publications and 245 images featured in our data gallery.

Browse primary antibodies for WB, ... View more Antibodies that detect BUBR1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry and ELISA. These antibodies target BUBR1 in Human, Mouse, Rat and Canine samples. Our BUBR1 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Sheep. These antibodies have been verified by Relative Expression to confirm specificity to BUBR1. Find the BUBR1 antibody that fits your needs. Choose from 1 of 53 BUBR1 antibodies, which have been validated in experiments with 6 publications and 245 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

BUBR1 is a member of the Ser/Thr protein kinase family. It is a component of the mitotic checkpoint that delays anaphase until all chromosome are properly attached to the mitotic spindle. Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to malignant transformations. Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1. They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions. hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early. BUBR1 has been detected in human cancers. It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.

Synonyms

AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1

Target Video

6320247778112

BUBR1 antibodies from Thermo Fisher Scientific

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Learn more about BUBR1 primary antibodies that can be used in Western Blot, Immunohistochemistry, Immunocytochemistry and Flow Cytometry in Human, Mouse, Rat and Dog samples.