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This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients.
C13orf18; KIAA0226 like; KIAA0226L; KIAA0226-like; Pacer; Protein associated with UVRAG as autophagy enhancer; Protein Rubicon-like; RGD1304929; RUBCNL; similar to chromosome 13 open reading frame 18; uncharacterized protein KIAA0226-like
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