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CD146 Antibodies

Antibodies that detect CD146 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry and ELISA. These antibodies target CD146 in Human, Mouse, Rat, Canine, Rabbit samples. Our CD146 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Goat. These antibodies have been verified by Relative expression to confirm specificity to CD146. Find the CD146 antibody that fits your needs. Choose from 1 of 83 CD146 antibodies, which have been validated in experiments with 124 publications and 394 images featured in our data gallery.

Browse primary antibodies for WB, ... View more Antibodies that detect CD146 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry and ELISA. These antibodies target CD146 in Human, Mouse, Rat, Canine, Rabbit samples. Our CD146 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Goat. These antibodies have been verified by Relative expression to confirm specificity to CD146. Find the CD146 antibody that fits your needs. Choose from 1 of 83 CD146 antibodies, which have been validated in experiments with 124 publications and 394 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

CD146 (MCAM) is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. CD146 is expressed at cell-cell junctions in all endothelial cells, and has also been observed in other normal and malignant cell types. In addition to its recognized role as a calcium-independent cell adhesion molecule, CD146 may also act as a signal transduction molecule in the recruitment of Fyn kinase, and in the subsequent tyrosine-phosphorylation of intracellular proteins involved in actin cytoskeleton assembly. CD146 plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. CD146 expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Further, CD146 could be an adhesion molecule active in neural crest cells during embryonic development. CD146 acts also as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.

Synonyms

1-gicerin; AV025631; CD146; CD149; Cell surface glycoprotein MUC18; cell surface glycoprotein P1H12; Gicerin; HEMCAM; l-gicerin; l-gicerin precursor; l-gicerin protein; LOW QUALITY PROTEIN: cell surface glycoprotein MUC18; MCAM; melanoma adhesion molecule; melanoma cell adhesion molecule; Melanoma-associated antigen A32; melanoma-associated antigen MUC18; Muc18; mucin-18; s-endo; S-endo 1 endothelial-associated antigen; s-gicerin; s-gicerin precursor

Target Video

6320251554112

CD146 antibodies from Thermo Fisher Scientific

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Learn more about CD146 primary antibodies that can be used in Immunohistochemistry, Western Blot, Flow Cytometry and Immunocytochemistry in Human, Mouse, Rat and Dog samples.