Anti-CD28 Antibodies

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CD28 Antibodies

Antibodies that detect CD28 can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Functional Assay. These antibodies target CD28 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our CD28 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Syrian Hamster, Goat, Hamster and Rat. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to CD28. Find the CD28 antibody that fits your needs. Choose from 1 of 119 CD28 antibodies, which have been validated in experiments with 1009 publications and 425 ... View more Antibodies that detect CD28 can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry, ELISA and Functional Assay. These antibodies target CD28 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our CD28 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit, Syrian Hamster, Goat, Hamster and Rat. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to CD28. Find the CD28 antibody that fits your needs. Choose from 1 of 119 CD28 antibodies, which have been validated in experiments with 1009 publications and 425 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. CD28 is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes. Moreover, CD28 is the critical T cell costimulatory receptor that provides the cell the important second activation signal by binding CD80 and CD86 which are expressed by antigen presenting cells. In addition to its co-stimulation role, CD28 functions by preventing T cells from entering an anergic-hyporesponsive state or from undergoing premature apoptotic cell death. In murine peripheral lymphoid organs and in the blood, all CD4+ and CD8+ T cells express CD28. In the thymus, CD28 expression is highest on immature CD3-, CD8+ and CD4+8+ cells, and on CD4-8- cells that express alpha/beta and gamma/delta TCR. The level of CD28 on mature CD4+ and CD8+ alpha/beta TCR+ thymocytes is two- to fourfold lower than on the immature cells. Diseases associated with CD28 dysfunction include mycosis fungiodes and Sezary's Disease.

Synonyms

antigen CD28; CD28; CD28 antigen; CD28 antigen (Tp44); CD28 isoform; CD28 isoform 2; Cd28 molecule; CD28 precursor protein; CD28 protein; CD28 protein precursor; CD28RNA; cell surface protein; CHT28; contains partial extracellular domain; costimulatory molecule B7 receptor CD28; EGK_04709; MGC138290; sCD28; soluble CD28; T44; T-cell costimulatory molecule CD28; T-cell costimulatory molecule Tp44; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28 homolog; TP44

Target Video

6320251467112

CD28 antibodies from Thermo Fisher Scientific

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Learn more about CD28 primary antibodies that can be used in Flow Cytometry, Western Blot, Immunohistochemistry and ELISA in Human, Mouse, Rat and Non-human primate samples.