CD298 Antibodies

Target Information

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.

Synonyms

AA409958; AI664000; Atp1b3; ATPase Na+/K+ transporting subunit beta 3; ATPase, Na+/K+ beta 3 polypeptide; ATPase, Na+/K+ transporting, beta 3 polypeptide; ATPase, Na+K+ transporting, beta polypeptide 3; ATPB-3; AW212096; CD298; CD298 antigen; Na K-ATPase beta-3 subunit; Na+/K+ -ATPase beta 3 subunit; NKAB3S; Sodium Potassium ATPase; Sodium/potassium-dependent ATPase subunit beta-3; sodium/potassium-transporting ATPase subunit beta-3