Anti-CD43 Antibodies

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CD43 Antibodies

Antibodies that detect CD43 can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and Immunoprecipitation. These antibodies target CD43 in Human, Rat, Mouse, Non-human primate and Ovine samples. Our CD43 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Rat. These antibodies have been verified by Relative Expression and Cell Treatment to confirm specificity to CD43. Find the CD43 antibody that fits your needs. Choose from 1 of 75 CD43 antibodies, which have been validated in experiments with 183 publications and 269 images featured in our data ... View more Antibodies that detect CD43 can be used in several scientific applications, including Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry and Immunoprecipitation. These antibodies target CD43 in Human, Rat, Mouse, Non-human primate and Ovine samples. Our CD43 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rabbit and Rat. These antibodies have been verified by Relative Expression and Cell Treatment to confirm specificity to CD43. Find the CD43 antibody that fits your needs. Choose from 1 of 75 CD43 antibodies, which have been validated in experiments with 183 publications and 269 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells. CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation. By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic. CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors. Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF deficiency CD43 promotes tumor proliferation and viability. CD43 appears to be an important modulator of leukocyte functions. Diseases associated with CD43 dysfunction include Wiscott-Aldrich Syndrome and Adenoid Basal Cell Carcinoma.

Synonyms

3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen

Target Video

6320251661112

CD43 antibodies from Thermo Fisher Scientific

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Learn more about CD43 primary antibodies that can be used in Flow Cytometry, Immunohistochemistry, Western Blot and Immunocytochemistry in Human, Mouse, Rat and Non-human primate samples.