IRAK1BP1 Antibodies

Antibodies that detect IRAK1BP1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target IRAK1BP1 in Mouse, Human and Rat samples. Our IRAK1BP1 polyclonal antibodies are developed in... Antibodies that detect IRAK1BP1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target IRAK1BP1 in Mouse, Human and Rat samples. Our IRAK1BP1 polyclonal antibodies are developed in Rabbit. Find the IRAK1BP1 antibody that fits your needs.... Antibodies that detect IRAK1BP1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target IRAK1BP1 in Mouse, Human and Rat samples. Our IRAK1BP1 polyclonal antibodies are developed in Rabbit. Find the IRAK1BP1 antibody that fits your needs. Choose from 1 of 4 IRAK1BP1 antibodies, which have been validated in experiments with 7 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us... Antibodies that detect IRAK1BP1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target IRAK1BP1 in Mouse, Human and Rat samples. Our IRAK1BP1 polyclonal antibodies are developed in Rabbit. Find the IRAK1BP1 antibody that fits your needs. Choose from 1 of 4 IRAK1BP1 antibodies, which have been validated in experiments with 7 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

SIMPL, also known as IRAK1BP1 (interleukin-1 receptor-associated kinase 1-binding protein 1), is a 260 amino acid protein belonging to the IRAK1BP1 family. In addition to containing an intrinsically disordered region which associates with HSPA1 and HSPA8, SIMPL also interacts directly with IRAK1 and promotes RELA transcriptional activity. SIMPL is a major component of the IRAK1-dependent TNFRSF1A signaling pathway in which TNF-alpha induces NF-kappa-B gene transcription, leading to an inhibition of proinflammatory cytokines. Inactivation of SIMPL inhibits tumor necrosis factor receptor type I-induced NF-kappaB activity. Localizing to the nucleus and cytoplasm, SIMPL requires the phosphorylation of Ser-56 and/or Ser-62 to be fully active.

Synonyms

4921528N06Rik; Aabp3; ActA binding protein 3; Acta-binding protein 70; AI851240; Aip70; interleukin 1 receptor associated kinase 1 binding protein 1; interleukin-1 receptor-associated kinase 1 binding protein 1; interleukin-1 receptor-associated kinase 1-binding protein 1; IRAK1-binding protein 1; Irak1bp1; MGC138458; MGC138460; PLK-interacting protein; signaling molecule that associates with the mouse pelle-like kinase; Simpl

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IRAK1BP1 Antibodies

Target Information

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