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NHE3 is a sodium/hydrogen exchanger in the brush border membrane of the proximal tubule, small intestine, and colon that plays a major role in transepithelial sodium absorption. SLC9A3R2, as well as SLC9A3R1 and protein kinase A phosphorylation, may play a role in NHE3 regulation.
0610011L07Rik; 1200011K07Rik; 2010007A20Rik; E3karp; HGNC:11076; MGC104639; Na(+)/H(+) exchange regulatory cofactor NHE-RF2; NHE3 kinase A regulatory protein E3KARP; NHE3 regulatory factor 2; NHE3RF2; Nherf2; NHERF-2; OCTS2; SIP1; SIP-1; SLC9A3 regulator 2; SLC9A3R2; sodium/hydrogen exchanger; sodium/hydrogen exchanger 3 kinase A regulatory protein; Sodium-hydrogen exchanger regulatory factor 2; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2; solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2; solute carrier family 9 isoform 3 regulator 2; solute carrier family 9 isoform 3 regulator 2, isoform A; sodium/hydrogen exchanger; solute carrier family 9 isoform A3 regulatory factor 2; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2; Sry interacting protein 1; SRY-interacting protein 1; Sryip1; TKA-1; tyrosine kinase activator protein 1
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