p53AIP1 Antibodies

Antibodies that detect p53AIP1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target p53AIP1 in Human, Mouse and Rat samples. Our p53AIP1 polyclonal antibodies are developed in... Antibodies that detect p53AIP1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target p53AIP1 in Human, Mouse and Rat samples. Our p53AIP1 polyclonal antibodies are developed in Rabbit. Find the p53AIP1 antibody that fits your needs.... Antibodies that detect p53AIP1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target p53AIP1 in Human, Mouse and Rat samples. Our p53AIP1 polyclonal antibodies are developed in Rabbit. Find the p53AIP1 antibody that fits your needs. Choose from 1 of 6 p53AIP1 antibodies, which have been validated in experiments with 2 publications and 11 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for,... Antibodies that detect p53AIP1 can be used in several scientific applications, including Immunohistochemistry, Western Blot, ELISA and Immunocytochemistry. These antibodies target p53AIP1 in Human, Mouse and Rat samples. Our p53AIP1 polyclonal antibodies are developed in Rabbit. Find the p53AIP1 antibody that fits your needs. Choose from 1 of 6 p53AIP1 antibodies, which have been validated in experiments with 2 publications and 11 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

The novel protein p53AIP, p53-regulated apoptosis-inducing protein 1, has been identified from the direct cloning of p53 binding sequences from human genomic DNA. The expression of p53AIP1 in mitochondria is induced by wild-type p53, which leads to apoptotic cell death through dissipation of mitochondrial Dym. Severe DNA damage causes the phosphorylation of p53 at Ser-46, p53AIP1 expression, and apoptotic cell death. DNA damage-inducible apoptotic cell death was enhanced through transcriptional activation of p53AIP1. P53R2 is directly regulated by p53 for supplying nucleotides to repair damaged DNA, thus plays a pivotal role in cell survival by repairing damaged DNA in the nucleus and that dysfunction of this pathway might result in activation of p53 dependent apoptosis to eliminate dangerous cells. In the opposite, p53AIP1 is likely to play an important role in mediating p53-dependent apoptosis, and phosphorylation of Ser46 regulates the transcriptional activation of this apoptosis inducing gene.

Synonyms

p53AIP1; p53-regulated apoptosis-inducing protein 1; TP53AIP1; tumor protein p53 regulated apoptosis inducing protein 1

p53AIP1 Antibodies

Target Information

Synonyms

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