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E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843). Plays also a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514). [UniProt]
E3 ubiquitin-protein ligase RNF182; ring finger protein 182; RING-type E3 ubiquitin transferase RNF182; RNF182
100 µL
100 µL
100 µg
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