Antibodies that detect SOX17 can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), ELISA and Flow Cytometry. These antibodies target SOX17 in Human, Canine, Mouse, Rat and Non-human primate samples. Our SOX17 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Relative expression to confirm specificity to SOX17. Find the SOX17 antibody that fits your needs. Choose from 1 of 31 SOX17 antibodies, which have been validated in experiments with 7 publications and 122 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
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SOX17 (transcription factor SOX-17) belongs to the SRY-related HMB box family of transcription factors. It acts as a transcription regulator that binds target promoter DNA and bends the DNA. It binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. SOX17 modulates transcriptional regulation via WNT3A and inhibits Wnt signaling. It promotes degradation of activated CTNNB1. SOX17 plays an essential role in the regulation of embryonic development and is required for normal looping of the embryonic hear tube and for normal development of the definitive gut endoderm. Mutations in the gene can result in vesicoureteral reflux.
SRY (sex determining region Y)-box 17; SRY box 17; SRY-box containing gene 17; SRY-related HMG-box transcription factor SOX17; Transcription factor SOX-17
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
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