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Proteintech

MIG6/ERRFI1 Polyclonal Antibody

24 References
View all (10) Mig-6 antibodies

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MIG6/ERRFI1 Polyclonal Antibody

Product Details

11630-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 11 publications 11 publications

Immunohistochemistry (IHC)

-
View 7 publications 7 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:20-1:200
View 3 publications 3 publications

Immunoprecipitation (IP)

-
View 1 publication 1 publication

Miscellaneous PubMed (Misc)

-
View 1 publication 1 publication

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MIG6; ERRFI1 Fusion Protein Ag2202 (113-462 aa encoded by BC025337)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Amount

40.5 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: CGFKKLTVN GVCASTPPLT PIKNSPSLFP CAPLCERGSR PLPPLPISEA LSLDDTDCEV EFLTSSDTDF LLEDSTLSDF KYDVPGRRSF RGCGQINYAY FDTPAVSAAD LSYVSDQNGG VPDPNPPPPQ THRRLRRSHS GPAGSFNKPA IRISNCCIHR ASPNSDEDKP EVPPRVPIPP RPVKPDYRRW SAEVTSSTYS DEDRPPKVPP REPLSPSNSR TPSPKSLPSY LNGVMPPTQS FAPDPKYVSS KALQRQNSEG SASKVPCILP IIENGKKVSS THYYLLPERP PYLDKYEKFF REAEETNGGA QIQPLPADCG ISSATEKPDS KTKMDLGGHV KRKHLSYVVS P (113-462 aa encoded by BC025337)

Target Information

ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: ERBB receptor feedback inhibitor 1; Gene 33 polypeptide; MIG-6; Mitogen-inducible gene 6 protein; Mitogen-inducible gene 6 protein homolog; RALT; Receptor-associated late transducer; unnamed protein product

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Gene Aliases: 1300002F13Rik; RALT; 33; AI788755; ERRFI1; gene 33; GENE-33; MIG-6; MIG6; Ralt; RGD1307599; Xxx

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UniProt ID: (Human) Q9UJM3, (Mouse) Q99JZ7, (Rat) P05432

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Entrez Gene ID: (Human) 54206, (Mouse) 74155, (Rat) 313729

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Function(s)
GTPase activator activity protein binding SH3 domain binding kinase binding protein kinase binding small GTPase binding
Process(es)
negative regulation of epidermal growth factor-activated receptor activity stress-activated protein kinase signaling cascade negative regulation of protein autophosphorylation negative regulation of interleukin-1 beta production negative regulation of collagen biosynthetic process negative regulation of epidermal growth factor receptor signaling pathway negative regulation of tumor necrosis factor biosynthetic process skin morphogenesis regulation of keratinocyte differentiation lung alveolus development negative regulation of peptidyl-tyrosine phosphorylation lung vasculature development lung epithelium development regulation of type B pancreatic cell proliferation negative regulation of ERK1 and ERK2 cascade negative regulation of cardiac muscle hypertrophy in response to stress cellular response to insulin stimulus cellular response to platelet-derived growth factor stimulus cellular response to epidermal growth factor stimulus cellular hyperosmotic response cellular response to dexamethasone stimulus skeletal system development liver development tissue homeostasis glucose metabolic process lipid metabolic process bile acid biosynthetic process apoptotic process epidermal growth factor receptor signaling pathway embryo implantation cholesterol metabolic process response to xenobiotic stimulus gene expression cell migration response to estradiol response to progesterone negative regulation of tumor necrosis factor production response to insulin uterine epithelium development chondrocyte proliferation limb joint morphogenesis cholesterol homeostasis protein kinase B signaling skin development response to steroid hormone epithelial cell proliferation progesterone receptor signaling pathway cartilage development uterus development epithelium development fat pad development protein localization to plasma membrane response to 1-oleoyl-sn-glycerol 3-phosphate
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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