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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • HTR3A Antibodies

          Osenses

          5HT3A R Polyclonal Antibody

          2 References
          View all (24) HTR3A antibodies

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          Cite 5HT3A R Polyclonal Antibody

          • Antibody Testing Data (1)
          5HT3A R Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          5HT3A R Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          5HT3A R Antibody (OSS00108W-100UL) in WB

          WB on mouse brain lysate using Rabbit antibody to 5-HT3A R (OSS00108W) at 1:500 dilution. Incubated 30 min at RT with shake. Blocking: 0.5% LFDM in 1x PBS containing 0.1% Tween-20. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          5HT3A R Antibody in Western Blot (WB)

          Product Details

          OSS00108W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:2,000
          -

          Immunohistochemistry (IHC)

          1:300-1:2,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Mouse

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from the 1t extracellular domain of mouse 5HT3A receptor conjugated to blue carrier protein was used as the antigen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          The peptide shares 86% identity with rat sequence.

          Specificity of this antibody: 5HT3A receptor.

          Target Information

          The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: 5-HT-3; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT3 serotonin receptor; serotonin receptor; Serotonin receptor 3A; Serotonin-gated ion channel receptor; truncated receptor

          View more View less

          Gene Aliases: 5-HT3; 5ht3; Htr3; Htr3a

          View more View less

          UniProt ID: (Mouse) Q61226

          View more View less

          Entrez Gene ID: (Mouse) 15561

          View more View less

          Function(s)
          G-protein coupled serotonin receptor activity extracellular ligand-gated ion channel activity serotonin-activated cation-selective channel activity voltage-gated potassium channel activity ligand-gated ion channel activity serotonin binding ligand-gated ion channel
          Process(es)
          transport ion transport cation transport serotonin receptor signaling pathway regulation of ion transmembrane transport potassium ion transmembrane transport cation transmembrane transport
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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