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Proteintech
Follistatin Monoclonal Antibody (4E9B10)
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Product Details
60060-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
4E9B10
Immunogen
Follistatin Fusion Protein Ag0775 (1-344 aa encoded by BC004107)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MVRARHQPG GLCLLLLLLC QFMEDRSAQA GNCWLRQAKN GRCQVLYKTE LSKEECCSTG RLSTSWTEED VNDNTLFKWM IFNGGAPNCI PCKETCENVD CGPGKKCRMN KKNKPRCVCA PDCSNITWKG PVCGLDGKTY RNECALLKAR CKEQPELEVQ YQGRCKKTCR DVFCPGSSTC VVDQTNNAYC VTCNRICPEP ASSEQYLCGN DGVTYSSACH LRKATCLLGR SIGLAYEGKC IKAKSCEDIQ CTGGKKCLWD FKVGRGRCSL CDELCPDSKS DEPVCASDNA TYASECAMKE AACSSGVLLE VKHSGSCNSI SEDTEEEEED EDQDYSFPIS SILEW (1-344 aa encoded by BC004107)
Target Information
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Activin-binding protein; Follictatin; Follistatin; FS; FST
Gene Aliases: AL033346; FS; FST
UniProt ID: (Human) P19883, (Mouse) P47931
Entrez Gene ID: (Human) 10468, (Mouse) 14313
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
hematopoietic progenitor cell differentiation
gamete generation
pattern specification process
female gonad development
cell differentiation
BMP signaling pathway
regulation of BMP signaling pathway
negative regulation of epithelial cell differentiation
hair follicle morphogenesis
negative regulation of activin receptor signaling pathway
ameloblast differentiation
odontogenesis of dentin-containing tooth
keratinocyte proliferation
positive regulation of hair follicle development
cellular response to growth factor stimulus
negative regulation of cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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