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Proteintech
NCALD Monoclonal Antibody (6B4E10)
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Product Details
66088-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
6B4E10
Immunogen
NCALD Fusion Protein Ag18760 (1-193 aa encoded by BC036098)
Conjugate
Form
Liquid
Concentration
1.05 mg/mL
Amount
157.5 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to NCALD.
Immunogen sequence: MGKQNSKLR PEVMQDLLES TDFTEHEIQE WYKGFLRDCP SGHLSMEEFK KIYGNFFPYG DASKFAEHVF RTFDANGDGT IDFREFIIAL SVTSRGKLEQ KLKWAFSMYD LDGNGYISKA EMLEIVQAIY KMVSSVMKMP EDESTPEKRT EKIFRQMDTN RDGKLSMEEF IRGAKSDPSI VRLLQCDPSS AGQF (1-193 aa encoded by BC036098)
Target Information
This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Neurocalcin-delta; unnamed protein product
Gene Aliases: AI848120; D030020D09Rik; D15Ertd412e; NCALD
UniProt ID: (Human) P61601, (Rat) Q5PQN0, (Mouse) Q91X97
Entrez Gene ID: (Pig) 100156785, (Human) 83988, (Rat) 553106, (Mouse) 52589
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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