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Proteintech
Hemopexin Monoclonal Antibody (3A9D6)
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Product Details
66479-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3A9D6
Immunogen
Hemopexin Fusion Protein Ag8533 (45-254 aa encoded by BC005395)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: DVTERCSDG WSFDATTLDD NGTMLFFKGE FVWKSHKWDR ELISERWKNF PSPVDAAFRQ GHNSVFLIKG DKVWVYPPEK KEKGYPKLLQ DEFPGIPSPL DAAVECHRGE CQAEGVLFFQ GDREWFWDLA TGTMKERSWP AVGNCSSALR WLGRYYCFQG NQFLRFDPVR GEVPPRYPRD VRDYFMPCPG RGHGHRNGTG HGNSICAVAH I (45-254 aa encoded by BC005395)
Target Information
Hemopexin is a serum glycoprotein that binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Structurally, hemopexin consists of two similar halves of approximately two hundred amino acid residues connected by a histidine-rich hinge region. Each half is itself formed by the repetition of a basic unit of some 35 to 45 residues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Beta-1B-glycoprotein; Hemopexin; Hyaluronidase
Gene Aliases: HPX; Hpxn; HX
UniProt ID: (Pig) P50828, (Human) P02790, (Rat) P20059
Entrez Gene ID: (Pig) 396998, (Human) 3263, (Rat) 58917
cellular iron ion homeostasis
metabolic process
heme transport
positive regulation of immunoglobulin production
positive regulation of humoral immune response mediated by circulating immunoglobulin
receptor-mediated endocytosis
viral process
hemoglobin metabolic process
heme metabolic process
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of interferon-gamma-mediated signaling pathway
transport
regulation of protein metabolic process
positive regulation of response to interferon-gamma
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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