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Proteintech
SLC31A1 Monoclonal Antibody (1A4H5)
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Product Details
67221-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1A4H5
Immunogen
SLC31A1 Fusion Protein Ag28410
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Amount
150 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
The trace metal copper (Cu) plays a crucial role in mammalian cells as a cofactor for many enzymes. Cu-related genetic diseases, such as Menkes disease and Wilson disease, arise from a lack of Cu homeostasis in mammalian cells. CTR1 is a high-affinity copper-uptake protein. The C-terminal domain is similar to the Raf family of protein kinases, but it's first two-thirds encodes a novel protein domain. CTR1 provides the primary avenue for copper uptake in mammalian cells, thereby, affecting Cu homeostasis and embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: copper transport 1 homolog; Copper transporter 1; hCTR1; High affinity copper uptake protein 1; solute carrier family 31 (copper transporter), member 1; solute carrier family 31 (copper transporters), member 1; Solute carrier family 31 member 1; unnamed protein product
Gene Aliases: COPT1; CTR1; NSCT; SLC31A1
UniProt ID: (Human) O15431
Entrez Gene ID: (Human) 1317
angiogenesis
ion transport
copper ion transport
cellular copper ion homeostasis
copper ion import
plasma membrane copper ion transport
copper ion transmembrane transport
vascular endothelial growth factor receptor-2 signaling pathway
xenobiotic transport
protein oligomerization
establishment of localization in cell
silver ion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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