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Proteintech
TTPA Monoclonal Antibody (3E7D10)
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Product Details
67431-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
3E7D10
Immunogen
TTPA Fusion Protein Ag13587
Conjugate
Form
Liquid
Concentration
1000 µg/mL
Amount
150 µg
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha TTP; Alpha-tocopherol transfer protein; Alpha-TTP; tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency); Tocopherol transfer protein alpha
Gene Aliases: alpha-TTP; alphaTTP; ATTP; AVED; TPP1; TTP; TTP1; TTPA
UniProt ID: (Human) P49638, (Rat) P41034, (Mouse) Q8BWP5
Entrez Gene ID: (Human) 7274, (Pig) 100152248, (Rat) 25571, (Mouse) 50500
placenta development
embryonic placenta development
lipid metabolic process
response to toxic substance
vitamin E metabolic process
vitamin transport
negative regulation of establishment of blood-brain barrier
intermembrane lipid transfer
positive regulation of beta-amyloid clearance
response to nutrient
response to pH
developmental process
intermembrane transport
intracellular pH reduction
negative regulation of cell death
transport
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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