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Proteintech
CRMP5 Monoclonal Antibody (3F2D8)
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Product Details
68272-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
3F2D8
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: KVVLAETTTA HATLTGLHYY HQDWSHAAAY VTVPPLRLDT NTSTYLMSLL ANDTLNIVAS DHRPFTTKQK AMGKEDFTKI PHGVSGVQDR MSVIWERGVV GGKMDENRFV AVTSSNAAKL LNLYPRKGRI IPGADADVVV WDPEATKTIS ASTQVQGGDF NLYENMRCHG VPLVTISRGR VVYENGVFMC AEGTGKFCPL RSFPDTVYKK LVQREKTLKV RGVDRTPYLG DVAVVVHPGK KEMGTPLADT PTRPVTRHGG MRDLHESSFS LSGSQIDDHV PKRASARILA PPGGRSSGIW
Target Information
The collapsin response mediator protein (CRMP) family of proteins (also referred to as ULIP6) are a group of neurologic proteins that have been found to play key roles in growth cone guidance during neural development. CRMP5 has relatively low sequence homology with the other four members of the CRMP family. CRMP5 is expressed in the developing nervous system in an expression pattern that resembles CRMP2 and has a peak expression during the first postnatal week. Elevated levels of autoantibody to CRMP5 have been shown to be linked to paraneoplastic autoimmune optic neuritis and other paraneoplastic neoplasms. Auto-immunity against CRMP5 expression (predominantly the N-terminal epitopes) is also being investigated as an oncological marker in the respiratory system and in the thymus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collapsin response mediator protein 5; collapsin response mediator protein-5; CRAM; CRMP-5; CRMP3-associated molecule; Dihydropyrimidinase-related protein 5; DRP-5; ULIP-6; ULIP6 protein; UNC33-like phosphoprotein 6
Gene Aliases: CRAM; CRMP-5; CRMP5; CV2; DPYSL5; RTSC4; ULIP6
UniProt ID: (Human) Q9BPU6, (Rat) Q9JHU0, (Mouse) Q9EQF6
Entrez Gene ID: (Human) 56896, (Rabbit) 100353506, (Pig) 100511810, (Rat) 65208, (Mouse) 65254
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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