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Pan-KChIP K+ Channel Monoclonal Antibody (K55/82), FL490
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Product Details
75-006-FL490
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
K55/82
Immunogen
Fusion protein amino acids 1-216 (full length) of rat KChIP1b (accession number Q8R426) produced recombinantly in E. Coli.
Conjugate
Excitation/Emission Max
491/515 nm
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
Pan-KChIP refers to the collective group of Kv Channel-Interacting Proteins (KChIPs), which are auxiliary subunits that associate with voltage-gated potassium (Kv) channels. These proteins modulate the trafficking, surface expression, and functional properties of Kv channels, thereby influencing neuronal excitability and signaling. Dysregulation of KChIPs has been implicated in various neurological conditions, including epilepsy and ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A-type potassium channel modulating protein 3; A-type potassium channel modulatory protein 1; A-type potassium channel modulatory protein 1.2; A-type potassium channel modulatory protein 2; A-type potassium channel modulatory protein 3; A-type potassium channel modulatory protein 4; A-type potassium channel modulatory protein KCNIP1; A-type potassium channel modulatory protein KCNIP2; alternatively spliced; calcium binding protein; Calsenilin; calsenilin presenilin-binding protein EF hand transcription factor; calsenilin, presenilin binding protein, EF hand transcription factor; calsenilin, presenilin-binding protein, EF hand transcription fa; calsenilin, presenilin-binding protein, EF hand transcription factor; Calsenilin-like protein; Cardiac voltage-gated potassium channel modulatory subunit; downstream regulatory element-antagonist modulator; DRE-antagonist modulator; DREAM; KChIP; KChIP1; KChIP2; KCHIP2.2; KChIP3; KChIP4; KChIP4bs; KCNIp1; KCNIP1-Ia#II; KCNIP1-Ib; KCNIP1-Ib#II; KCNIP1-Ib+75inV; KCNIP2-Ia; KCNIP2-Ia#IIab; KCNIP2-Ia#IIb; KCNIP2-Ib#IIab; KCNIP2-Ic#IIab; KCNIP3-Ia; KCNIP3-Ib#II; KCNIP4-Ia; KCNIP4-Ia#II; KCNIP4-Ib#II; KCNIP4-Ic#II; KCNIP4-Id#II; KCNIP4-Ie#II; Kv channel interacting protein 1; Kv channel interacting protein 2; Kv channel interacting protein 3, calsenilin; Kv channel interacting protein 4; Kv channel-interacting protein 1; Kv channel-interacting protein 2; Kv channel-interacting protein 3; Kv channel-interacting protein 4; neuronal calcium sensor-1 homolog; potassium channel auxiliary subunit KCHIP2; potassium channel interacting protein 1; potassium channel interacting protein 3; potassium channel interacting protein 4; potassium channel interacting protein; KChIP2; Potassium channel-interacting protein 1; Potassium channel-interacting protein 2; Potassium channel-interacting protein 4; recoverin-family member; unnamed protein product; VABP protein; Vesicle APC-binding protein
Gene Aliases: 4933407H12Rik; AI413860; AV032399; CALP; Calp250; CSEN; DREAM; KCHIP1; Kchip1.2; KCHIP2; KCHIP3; KCHIP4; KChIP4a; KCNIP1; KCNIP2; KCNIP3; KCNIP4; R74849; rKChIP3; VABP
UniProt ID: (Human) Q9NZI2, (Human) Q9NS61, (Human) Q9Y2W7, (Human) Q6PIL6, (Mouse) Q9JJ57, (Rat) Q8R426, (Mouse) Q9JJ69, (Rat) Q9JM59, (Mouse) Q9QXT8, (Rat) Q9JM47, (Rat) Q99MG9, (Mouse) Q6PHZ8
Entrez Gene ID: (Human) 30820, (Human) 30819, (Human) 30818, (Human) 80333, (Mouse) 70357, (Rat) 65023, (Mouse) 80906, (Rat) 56817, (Mouse) 56461, (Rat) 65199, (Rat) 259243, (Mouse) 80334
potassium channel activity
calcium ion binding
protein binding
potassium channel regulator activity
ion channel binding
metal ion binding
A-type (transient outward) potassium channel activity
identical protein binding
macromolecular complex binding
ER retention sequence binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
voltage-gated ion channel activity
protein heterodimerization activity
protein N-terminus binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
protein C-terminus binding
sequence-specific DNA binding
calcium-dependent protein binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
transport
ion transport
potassium ion transport
intracellular protein transport
apoptotic process
sensory perception of pain
regulation of ion transmembrane transport
regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
response to pain
behavioral response to pain
potassium ion transmembrane transport
protein localization to plasma membrane
regulation of potassium ion transmembrane transport
regulation of signal transduction
ion transmembrane transport
signal transduction
action potential
detection of calcium ion
muscle contraction
chemical synaptic transmission
regulation of heart contraction
clustering of voltage-gated potassium channels
regulation of membrane repolarization
membrane repolarization
membrane repolarization during cardiac muscle cell action potential
regulation of potassium ion export across plasma membrane
positive regulation of potassium ion export across plasma membrane
potassium ion export
protein heterooligomerization
positive regulation of action potential
potassium ion export across plasma membrane
biological_process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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